gene 1,593 words KG: GNAL
Contents

GNAL — Gαolf Subunit

🧬 Gene Info
Gene SymbolGNAL
Full NameGαolf Subunit
Chromosome18p11.21
Functionencodes the Gαolf protein (Guanine nucleotide-binding protein subunit alpha L), a member of the Gαs family of heterotrimeric G proteins
Primary ExpressionNeuron-specific (olfactory epithelium, striatum)
Molecular Weight44 kDa
Exons12
UniProt ID[P38405](https://www.uniprot.org/uniprot/P38405)
Ensembl IDENSG00000141449
GeneCardsGNAL
Human Protein AtlasGNAL
Chromosomal location18p11.21
Genomic span~67 kb, 12 exons
Associated DiseasesAls
InteractionsCAMKII, CCND1, CYTOKINES, IL1B, IL3, IL8
KG Connections145 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (187)

Synaptic Vesicle Tau Capture Inhibition
Score: 0.58
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
Tau-Independent Microtubule Stabilization via MAP6 Enhanceme
Score: 0.57
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.57
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.57
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
Circadian-Gated Maresin Biosynthesis Amplification
Score: 0.56
Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
Trans-Synaptic Adhesion Molecule Modulation
Score: 0.54
Temporal Decoupling via Circadian Clock Reset
Score: 0.54
Lysosomal Membrane Repair Enhancement
Score: 0.54
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
Blood-Brain Barrier SPM Shuttle System
Score: 0.53
Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.53
Cryptic Exon Silencing Restoration
Score: 0.53
Astrocytic Lactate Shuttle Enhancement for Grid Cell Bioener
Score: 0.53
Piezoelectric Nanochannel BBB Disruption
Score: 0.52
Vocal Cord Neuroplasticity Stimulation
Score: 0.52
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Synthetic Biology Approach: Designer Mitochondrial Export Sy
Score: 0.51
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Related Analyses (30)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

See Also (15)

ATP P2X3 Receptor Neurons
cell · KG edge: co_discussed
Amyotrophic Lateral Sclerosis
redirect · KG edge: co_discussed
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: co_discussed
Apoptosis in Neurodegeneration
entity · KG edge: co_discussed
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: co_discussed

Knowledge Graph (12 edges)

GNAL expressed_in VAMP7
GNAL expressed_in MMP9
GNAL inhibits PI3K
GNAL associated_with AKT
GNAL associated_with AKT1
GNAL expressed_in MCC
GNAL expressed_in CXCR4
GNAL associated_with ALDH1A3
GCH1 associated_with GNAL
THAP1 associated_with GNAL

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