gene 1,894 words KG: ALDH1A3
Contents

ALDH1A3 — Aldehyde Dehydrogenase 1 Family Member A3

🧬 Gene Info
Gene SymbolAldehyde Dehydrogenase 1 Family Member A3
Chromosome15q26.3
Protein FamilyAldehyde dehydrogenase (ALDH) family
Protein TypeEnzyme
Functionis a member of the ALDH superfamily, which encompasses enzymes that catalyze the NAD(P)-dependent oxidation of aldehydes to carboxylic acids.
Molecular Weight56 kDa
Amino Acids512 aa
Gene TypeProtein-coding
UniProt IDP47820
NCBI Gene ID220
Ensembl IDENSG00000184254
OMIM610463
InteractionsGLIOBLASTOMA, XRCC1
KG Connections22 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

Chromatin Accessibility Restoration via BRD4 Modulation
Score: 0.77
Epigenetic Memory Erasure via TET2 Activation
Score: 0.74
TET2-Mediated Demethylation Rejuvenation Therapy
Score: 0.71
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.66
KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
Oligodendrocyte White Matter Vulnerability
Score: 0.65

Related Analyses (4)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Epigenetic clocks and biological aging in neurodegeneration
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (6)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Epigenetic Dysregulation Validation in Parkinson's Disease
clinical · proposed · Score: 0.40
AAV-LRRK2 Gene Therapy IND-Enabling Study Design
clinical · proposed · Score: 0.40
Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40

See Also (11)

Neurodegeneration
disease · KG edge: implicated_in
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: expressed_in
AKT1 Gene
gene · KG edge: associated_with
CXCR4 Gene
gene · KG edge: expressed_in
GNAL — Gαolf Subunit
gene · KG edge: associated_with

Knowledge Graph (12 edges)

GNAL associated_with ALDH1A3
VAMP7 expressed_in ALDH1A3
MMP9 expressed_in ALDH1A3
PI3K expressed_in ALDH1A3
AKT associated_with ALDH1A3
AKT1 associated_with ALDH1A3
MCC expressed_in ALDH1A3
CXCR4 expressed_in ALDH1A3
ALDH1A3 activates XRCC1
XRCC1 activates ALDH1A3

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