gene 2,169 words KG: THAP1
Contents

THAP1 Gene

🧬 Gene Info
Gene SymbolTHAP1
Full NameTHAP Domain Containing 1
Chromosome8p21.2
Protein TypeTranscription Factor
Functionencodes a zinc finger transcription factor belonging to the THAP (THANATOS-associated protein) family.
Primary ExpressionBrain, testis, blood, endothelium
Amino Acids342 aa
Exons11
UniProt IDQ9NVX4
NCBI Gene ID55145
GeneCardsTHAP1
Human Protein AtlasTHAP1
Human THAP1342 amino acids
Mouse Thap195% amino acid identity
Zebrafish thap178% identity
Associated DiseasesAls
KG Connections8 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (8)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.38
Digital Twin-Guided Metabolic Reprogramming
Score: 0.55
CYP46A1 Overexpression Gene Therapy
Score: 0.92
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
PARP1 Inhibition Therapy
Score: 0.74

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (7)

Neurodegeneration
disease · KG edge: implicated_in
ANO3 Gene
gene · KG edge: associated_with
GCH1 Gene
gene · KG edge: associated_with
GNAL — Gαolf Subunit
gene · KG edge: associated_with
TOR1A Gene
gene · KG edge: associated_with

Knowledge Graph (8 edges)

GCH1 associated_with THAP1
THAP1 associated_with ANO3
THAP1 associated_with GNAL
THAP1 associated_with TOR1A
THAP1 contributes_to ANXIETY
THAP1 contributes_to DEPRESSION
THAP1 associated_with Als
THAP1 contributes_to Actin

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