gene 746 words KG: GABARAP
Contents

GABARAP Gene

🧬 Gene Info
Gene SymbolGABARAP
Full NameGABA Type A Receptor Associated Protein
Chromosome17p13.1
FunctionGABARAP is a member of the ATG8 family (MAP1LC3/GABARAP family) with multiple cellular functions
PathwaysAkt, Autophagy, Endocytosis, Er Stress, Lysosomal Degradation
UniProt IDO95166
NCBI Gene ID23710
Ensembl IDENSG00000138967
OMIM607418
GeneCardsGABARAP
Human Protein AtlasGABARAP
Associated DiseasesAls, Alzheimer, Amyotrophic Lateral Sclerosis, Ataxia, Cancer
Known Drugs/Compoundsrapamycin
InteractionsActin, AKT1, AKT1S1, AMBRA1, AMPK, AMYLOID
KG Connections969 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (16)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.78
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
APOE Isoform Expression Across Glial Subtypes
Score: 0.74
SIRT3-Mediated Mitochondrial Deacetylation Failure with PINK
Score: 0.74

Related Analyses (9)

Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived

See Also (10)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: interacts_with
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: associated_with
ACTB Gene
gene · KG edge: associated_with
AKT1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

OPTN interacts_with GABARAP
CASP3 interacts_with GABARAP
AKT1 interacts_with GABARAP
CALCOCO2 interacts_with GABARAP
CGAS interacts_with GABARAP
CFTR interacts_with GABARAP
SQSTM1 interacts_with GABARAP
RPS6KB1 interacts_with GABARAP
GRB2 interacts_with GABARAP
RHEB interacts_with GABARAP

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