| Gene Symbol | CGAS |
| Chromosome | 6q15 |
| Protein Type | Enzyme |
| Target Class | Enzyme |
| Function | Small molecule inhibitor of cyclic dinucleotide synthesis |
| Mechanism of Action | Small molecule inhibitor of cyclic dinucleotide synthesis |
| Druggability | Medium (0.47) |
| Clinical Stage | Phase III |
| Molecular Weight | 57 kDa |
| Amino Acids | 522 aa |
| Exons | 8 |
| Pathways | Akt, Amyloid, Apoptosis, Autophagy, Calcium Signaling |
| UniProt ID | Q8N884 |
| NCBI Gene ID | 115004 |
| Ensembl ID | ENSG00000154122 |
| GeneCards | CGAS |
| Human Protein Atlas | CGAS |
| Associated Diseases | aging, Als, Alzheimer |
| Known Drugs/Compounds | Aberrant DNA, cGAS Inhibitors, Ginkgetin, Mitochondrial Dna, Mitochondrial DNA, mtDNA |
| Interactions | ACHE, Actin, AD, AGING, AHR, AKT |
| SciDEX Target | View Target Profile (4 clinical trials) |
| KG Connections | 1976 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!