concept

PDLIM5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PDLIM5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

66Connections

0Hypotheses

0Analyses

37Outgoing

29Incoming

0Experiments

0Debates

Summary

PDLIM5 is a concept in neurodegeneration research. Key relationships include: associated with, expressed in. Associated with ALS, Als, BIPOLAR_DISORDER. Connected to 47 entities in the SciDEX knowledge graph.

View on Wiki →

No AI portrait yet

💡 Concept Info

Name	PDLIM5
Key Genes/Proteins	AND, App, Bdnf, BDNF, BMAL1, CIRCADIAN RHYTHM
Related Diseases	Als, ALS, Bipolar, BIPOLAR_DISORDER, Depression
Related Pathways	Circadian Rhythm

Pathway Diagram

graph TD
    PDLIM5["PDLIM5"]
    PDLIM5 -->|"expressed in"| Bipolar["Bipolar"]
    PDLIM5 -->|"expressed in"| MTDNA["MTDNA"]
    PDLIM5 -->|"expressed in"| DNA["DNA"]
    DNA -->|"expressed in"| PDLIM5
    MTDNA -->|"expressed in"| PDLIM5
    AND["AND"] -->|"expressed in"| PDLIM5

Outgoing (37)

Target	Relation	Type	Str
ALS	associated_with	disease	0.65
Als	associated_with	disease	0.65
Ms	associated_with	disease	0.65
Depression	associated_with	disease	0.65
Bipolar	expressed_in	disease	0.65
Schizophrenia	associated_with	disease	0.65
DNA	expressed_in	gene	0.60
FKBP5	associated_with	gene	0.60
SYNGR1	associated_with	gene	0.60
TPH2	associated_with	gene	0.60
Circadian Rhythm	associated_with	pathway	0.60
DEPRESSION	associated_with	gene	0.60
RGS4	associated_with	gene	0.60
GRM4	associated_with	gene	0.60
NCAM1	associated_with	gene	0.60
DISC1	associated_with	gene	0.60
POLG	associated_with	gene	0.60
MTDNA	expressed_in	gene	0.60
AND	expressed_in	gene	0.60
Rb	associated_with	protein	0.60
App	associated_with	protein	0.60
Bdnf	associated_with	protein	0.60
CIRCADIAN RHYTHM	associated_with	gene	0.60
G72	associated_with	gene	0.60
GENES	associated_with	gene	0.60
BMAL1	associated_with	gene	0.60
GRIN2B	associated_with	gene	0.60
HTR2A	associated_with	gene	0.60
PERIOD3	associated_with	gene	0.60
DRD1	associated_with	gene	0.60
HTTLPR	associated_with	gene	0.60
BDNF	associated_with	gene	0.60
DAO	associated_with	gene	0.60
NRG1	associated_with	gene	0.60
TRPM2	associated_with	gene	0.60
BIPOLAR_DISORDER	associated_with	disease	0.50
GENE EXPRESSION	expressed_in	concept	0.50

Incoming (29)

Source	Relation	Type	Str
HTTLPR	associated_with	gene	0.60
MITOCHONDRIAL DNA	associated_with	gene	0.60
BDNF	associated_with	gene	0.60
PERIOD3	associated_with	gene	0.60
HTR2A	associated_with	gene	0.60
GRM4	associated_with	gene	0.60
G72	associated_with	gene	0.60
TRPM2	associated_with	gene	0.60
GENES	associated_with	gene	0.60
DRD1	associated_with	gene	0.60
BMAL1	associated_with	gene	0.60
GABRA5	associated_with	gene	0.60
GRM3	associated_with	gene	0.60
DAO	associated_with	gene	0.60
NRG1	associated_with	gene	0.60
GRIN2B	associated_with	gene	0.60
DNA	expressed_in	gene	0.60
NCAM1	associated_with	gene	0.60
RGS4	associated_with	gene	0.60
DEPRESSION	associated_with	gene	0.60
FKBP5	associated_with	gene	0.60
DISC1	associated_with	gene	0.60
POLG	associated_with	gene	0.60
SYNGR1	associated_with	gene	0.60
AND	expressed_in	gene	0.60
MTDNA	expressed_in	gene	0.60
CIRCADIAN RHYTHM	associated_with	gene	0.60
TPH2	associated_with	gene	0.60
Bipolar	expressed_in	disease	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning PDLIM5 in their description or question text

No additional research found