Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MMSE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | MMSE |
| Key Genes/Proteins | AMYLOID, APP, CLU, CR1 |
| Related Diseases | AGING, ALZHEIMER, ALZHEIMER'S DISEASE, COGNITIVE DECLINE, CSF |
Knowledge base pages for this entity
graph TD
MMSE[MMSE]
MMSE -->|regulates| DIABETES[DIABETES]
MMSE ---|associated| TH[TH]
MMSE ---|associated| APP[APP]
MMSE ---|associated| CLU[CLU]
MMSE ---|associated| CR1[CR1]
MMSE ---|associated| ROS[ROS]
MMSE ---|associated| CSF[CSF]
TAU[TAU] -->|stabilizes| MMSE
DASATINIB[DASATINIB] ---|associated| MMSE
ENTORHINAL_CORTEX[ENTORHINAL CORTEX] ---|associated| MMSE
CORTEX[CORTEX] ---|associated| MMSE
ASTROCYTE[ASTROCYTE] ---|associated| MMSE
NEURON[NEURON] ---|associated| MMSE
ALZHEIMER_S_DISEASE[ALZHEIMER'S DISEASE] ---|associated| MMSE| Source | Relation | Type | Str |
|---|---|---|---|
| TAU | stabilizes | protein | 0.60 |
| DASATINIB | associated_with | drug | 0.50 |
| ASTROCYTES | associated_with | cell_type | 0.50 |
| QUERCETIN | associated_with | drug | 0.50 |
| MICROGLIA | associated_with | cell_type | 0.50 |
| NEUROINFLAMMATION | associated_with | phenotype | 0.50 |
| INFLAMMATION | associated_with | phenotype | 0.50 |
| AGING | associated_with | phenotype | 0.50 |
| DIABETES | associated_with | disease | 0.50 |
| ENTORHINAL CORTEX | associated_with | brain_region | 0.50 |
| CORTEX | associated_with | brain_region | 0.50 |
| ASTROCYTE | associated_with | cell_type | 0.50 |
| NEURON | associated_with | cell_type | 0.50 |
| ALZHEIMER'S DISEASE | associated_with | disease | 0.50 |
| ALZHEIMER | associated_with | disease | 0.50 |
| MICROGLIAL ACTIVATION | associated_with | phenotype | 0.50 |
| COGNITIVE DECLINE | associated_with | phenotype | 0.50 |
| OXIDATIVE STRESS | associated_with | phenotype | 0.50 |
| SYNAPTIC LOSS | associated_with | phenotype | 0.50 |
| HIPPOCAMPUS | associated_with | brain_region | 0.50 |
| SENESCENCE | associated_with | phenotype | 0.50 |
| AMYLOID | associated_with | protein | 0.45 |
| DONANEMAB | associated_with | drug | 0.45 |
| DEMENTIA | associated_with | disease | 0.45 |
| IL18 | associated_with | gene | 0.45 |
| CYTOKINES | associated_with | phenotype | 0.45 |
| NEURODEGENERATION | associated_with | phenotype | 0.45 |
| IL10 | associated_with | gene | 0.45 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning MMSE in their description or question text
No additional research found