Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about EPITHELIAL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | EPITHELIAL |
graph TD
EPITHELIAL["EPITHELIAL"]
style EPITHELIAL fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
EPITHELIAL -->|"expressed in"| Basal_Ganglia((Basal Ganglia))
EPITHELIAL -->|"expressed in"| Gray_Matter((Gray Matter))
EPITHELIAL -->|"expressed in"| Brainstem((Brainstem))
EPITHELIAL -->|"expressed in"| Substantia_Nigra((Substantia Nigra))
CPT1A([CPT1A]) -->|"regulates"| EPITHELIAL
MITOCHONDRIA([MITOCHONDRIA]) -->|"activates"| EPITHELIAL
SQSTM1([SQSTM1]) -->|"regulates"| EPITHELIAL
PPARG([PPARG]) -->|"regulates"| EPITHELIAL
RPS6KB1([RPS6KB1]) -->|"regulates"| EPITHELIAL
LRP2([LRP2]) -->|"regulates"| EPITHELIAL
NADH([NADH]) -->|"regulates"| EPITHELIAL
ATG([ATG]) -->|"regulates"| EPITHELIAL
PPARA([PPARA]) -->|"regulates"| EPITHELIAL
EIF4EBP1([EIF4EBP1]) -->|"regulates"| EPITHELIAL| Target | Relation | Type | Str |
|---|---|---|---|
| Brainstem | expressed_in | brain_region | 0.50 |
| Basal Ganglia | expressed_in | brain_region | 0.50 |
| Gray Matter | expressed_in | brain_region | 0.50 |
| Substantia Nigra | expressed_in | brain_region | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| MITOCHONDRIA | activates | gene | 0.60 |
| SQSTM1 | regulates | gene | 0.60 |
| PPARG | regulates | gene | 0.60 |
| RPS6KB1 | regulates | gene | 0.60 |
| LRP2 | regulates | gene | 0.60 |
| NADH | regulates | gene | 0.60 |
| ATG | regulates | gene | 0.60 |
| PPARA | regulates | gene | 0.60 |
| EIF4EBP1 | regulates | gene | 0.60 |
| MTOR | regulates | gene | 0.60 |
| MAP1LC3B | regulates | gene | 0.60 |
| RUBCN | regulates | gene | 0.60 |
| RAB7A | regulates | gene | 0.60 |
| PIK3C3 | regulates | gene | 0.60 |
| SREBF1 | regulates | gene | 0.60 |
| RAS | regulates | gene | 0.60 |
| EGFR | regulates | gene | 0.60 |
| CTSD | regulates | gene | 0.60 |
| MTORC1 | regulates | gene | 0.60 |
| ACTB | regulates | gene | 0.60 |
| LAMP1 | regulates | gene | 0.60 |
| ATP | regulates | gene | 0.60 |
| PPARGC1A | regulates | gene | 0.60 |
| EIF2AK3 | interacts_with | gene | 0.60 |
| SQSTM1 | interacts_with | gene | 0.60 |
| HMGB1 | interacts_with | gene | 0.60 |
| OPTINEURIN | interacts_with | gene | 0.60 |
| PPARG | interacts_with | gene | 0.60 |
| WNT | regulates | gene | 0.60 |
| APC | regulates | gene | 0.60 |
| ATF6 | regulates | gene | 0.60 |
| RPS6KB1 | interacts_with | gene | 0.60 |
| GABA | interacts_with | gene | 0.60 |
| STING1 | interacts_with | gene | 0.60 |
| AMPK | regulates | gene | 0.60 |
| MLKL | interacts_with | gene | 0.60 |
| RIPK1 | interacts_with | gene | 0.60 |
| MTOR | interacts_with | gene | 0.60 |
| EGF | interacts_with | gene | 0.60 |
| RB1 | interacts_with | gene | 0.60 |
| HSP70 | interacts_with | gene | 0.60 |
| ATG16L1 | regulates | gene | 0.60 |
| AKT1S1 | regulates | gene | 0.60 |
| RHEB | interacts_with | gene | 0.60 |
| ERN1 | interacts_with | gene | 0.60 |
| GABARAP | interacts_with | gene | 0.60 |
| LRRK2 | interacts_with | gene | 0.60 |
| DEPTOR | interacts_with | gene | 0.60 |
| CGAS | regulates | gene | 0.60 |
| CPT1A | regulates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning EPITHELIAL in their description or question text
No additional research found