SciDEX — CARDIOMYOCYTES

Target	Relation	Type	Str
OXIDATIVE STRESS	inhibits	process	0.80
NRF2	regulates	gene	0.65
NRF2	causes	gene	0.65
OXIDATIVE STRESS	causes	phenotype	0.65
DOXORUBICIN	associated_with	drug	0.50
FERROPTOSIS	associated_with	process	0.50
FERROPTOSIS	regulates	process	0.50
FERROPTOSIS	inhibits	process	0.50
STEM CELLS	activates	cell_type	0.50
FERROPTOSIS	activates	process	0.50
CANAGLIFLOZIN	associated_with	drug	0.45
MELATONIN	associated_with	drug	0.45
RIBOSOME	associated_with	organelle	0.45
CGAS	inhibits	gene	0.35
STING	implicated_in	gene	0.35
GPX4	implicated_in	gene	0.35
PI3K	activates	gene	0.35
PI3K/AKT SIGNALING	inhibits	process	0.35
HEART FAILURE	activates	disease	0.35
NRF2 SIGNALING	inhibits	process	0.35
HDAC3	inhibits	gene	0.35
ROS	activates	protein	0.35
OXIDATIVE STRESS	activates	process	0.35
NF-KB	activates	gene	0.35
ERK	activates	gene	0.35
SIRT1	interacts_with	gene	0.35
STEM CELLS	differentiates_to	cell_type	0.35
ISCHEMIA	activates	disease	0.35
FERROPTOSIS	causes	process	0.35
FERROPTOSIS	protects_against	process	0.35
DIABETES	interacts_with	disease	0.35
SENESCENCE	regulates	process	0.35
IPSC	activates	cell_type	0.35
INFLAMMATION	interacts_with	process	0.35
CYTOKINES	inhibits	protein	0.35
ISCHEMIA	inhibits	disease	0.35
VEGF	inhibits	gene	0.35
DIABETES	activates	disease	0.35
STING	inhibits	gene	0.35

Source	Relation	Type	Str
LAMP2B	expressed_in	protein	0.85
APOPTOSIS	activates	process	0.65
ROS	treats	phenotype	0.65
AKT	causes	gene	0.65
BDNF	produces	gene	0.65
OXIDATIVE STRESS	stabilizes	phenotype	0.60
ferroptosis	activates	phenotype	0.50
APOPTOSIS	inhibits	process	0.50
NRF2	inhibits	gene	0.50
Cardiac	inhibits	disease	0.50
apoptosis	inhibits	process	0.50
RAGE	activates	gene	0.50
oxidative stress	activates	phenotype	0.50
NF-κB	activates	concept	0.50
SIRT1	protects_against	gene	0.50
Stem Cell	associated_with	cell_type	0.50
TRKB	regulates	gene	0.50
TRKB	activates	gene	0.50
ferroptosis	regulates	phenotype	0.50
CELL DEATH	regulates	concept	0.50
aging	associated_with	phenotype	0.50
Cellular Senescence	associated_with	cell_type	0.50
LMNA	activates	gene	0.50
Stem Cell	activates	cell_type	0.50
IPSC	activates	concept	0.50
GENE EXPRESSION	regulates	concept	0.50
CCL2	inhibits	protein	0.50
ISCHEMIA	inhibits	disease	0.50
CYTOKINES	inhibits	concept	0.50
MTORC1	inhibits	concept	0.50
PROINFLAMMATORY CYTOKINES	inhibits	concept	0.50
cardiomyopathy	activates	disease	0.50
PERK	activates	gene	0.50
Autophagy	activates	process	0.50
VEGF	activates	gene	0.50
GRP78	activates	protein	0.50
DIABETES	activates	disease	0.50
Cardiac	activates	disease	0.50
DIABETES MELLITUS	activates	concept	0.50
Type 1 Diabetes	activates	disease	0.50
CGAS	inhibits	protein	0.50
STING	inhibits	gene	0.50
oxidative stress	inhibits	phenotype	0.50
ferroptosis	inhibits	phenotype	0.50
apoptosis	activates	process	0.50
PLEC	activates	gene	0.50
ALZHEIMER	activates	gene	0.50
Alzheimer'S Disease	activates	disease	0.50
Astrocytes	activates	cell_type	0.50
Heart Failure	activates	disease	0.50

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Title & PMID	Authors	Journal	Year	Citations
No papers found

Hypotheses and analyses mentioning CARDIOMYOCYTES in their description or question text

Name	CARDIOMYOCYTES
Key Genes/Proteins	AKT, ALZHEIMER, BCL2, BDNF
Related Diseases	aging, Alzheimer'S Disease, ALZHEIMER'S DISEASE

CARDIOMYOCYTES