Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about alzheimers: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
flowchart TD
alzheimers["alzheimers"]
ALZHEIMER(["ALZHEIMER"])
Cholesterol["Cholesterol"]
disease["disease"]
CHOLESTEROL_METABOLISM("CHOLESTEROL METABOLISM")
Microbiota("Microbiota")
Gut_Microbiota("Gut Microbiota")
alzheimers -->|"associated with"| ALZHEIMER
alzheimers -->|"activates"| ALZHEIMER
alzheimers -->|"activates"| Cholesterol
alzheimers -->|"activates"| disease
alzheimers -->|"activates"| CHOLESTEROL_METABOLISM
alzheimers -->|"associated with"| Microbiota
alzheimers -->|"associated with"| Gut_Microbiota
style alzheimers fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| WAM | activates | cell_type | 0.56 |
| ALZHEIMER | activates | gene | 0.50 |
| Cholesterol | activates | pathway | 0.50 |
| disease | activates | disease | 0.50 |
| ALZHEIMER | associated_with | gene | 0.50 |
| Microbiota | associated_with | process | 0.50 |
| Gut Microbiota | associated_with | process | 0.50 |
| CHOLESTEROL METABOLISM | activates | concept | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| TREM2 | associated_with | protein | 1.00 |
| DAM | associated_with | cell_type | 0.72 |
| MICROGLIA | participates_in | cell_type | 0.64 |
| SERPINA3N | associated_with | protein | 0.64 |
| R47H_TREM2 | contributes_to | protein | 0.64 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning alzheimers in their description or question text
No additional research found