gene 1,733 words KG: TRAF2
Contents

TRAF2 Gene

🧬 Gene Info
Gene SymbolTRAF2
Full NameTNF Receptor Associated Factor 2
Chromosome9q34.3
Protein TypeLigase
Functionencodes a critical E3 ubiquitin ligase that serves as a central adaptor protein in TNF receptor signaling pathways.
Molecular Weight56 kDa
Amino Acids522 aa
PathwaysNF-κB signaling, NF-κB, MAPK
UniProt IDQ9UAV6
NCBI Gene ID7186
Ensembl IDENSG00000126933
OMIM601985
GeneCardsTRAF2
Human Protein AtlasTRAF2
Associated DiseasesTumor
InteractionsActin, ACVR1, AKT, ALPK1, AMPK, AND
KG Connections158 knowledge graph edges
DatabasesGeneCardsHPASTRING

No AI portrait yet

Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Autophagosome Maturation Checkpoint Control
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
Glycine-Rich Domain Competitive Inhibition
Score: 0.64

Related Analyses (4)

Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with
ACVR1 Gene
gene · KG edge: interacts_with
BCL2 Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

TRAF2 activates TNF
TNF activates TRAF2
BCL2 associated_with TRAF2
FUNDC1 associated_with TRAF2
PARKIN associated_with TRAF2
UBIQUITIN associated_with TRAF2
TNF associated_with TRAF2
FIS1 associated_with TRAF2
SNAP29 associated_with TRAF2
LC3 associated_with TRAF2

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)