| Gene Symbol | FIS1 |
| Full Name | Fission 1 Mitochondrial Outer Membrane Protein |
| Chromosome | 7q22.1 |
| Protein Type | Mitochondrial outer membrane protein |
| Function | Fis1 Gene plays an important role in the study of neurodegenerative diseases |
| Molecular Weight | 17 kDa |
| Pathways | Apoptosis, Autophagy, Lysosomal Degradation, Mitochondrial Function, Mitophagy |
| GeneCards | FIS1 |
| Human Protein Atlas | FIS1 |
| N-terminal arm | Flexible region that regulates DRP1 interaction |
| Two TPR-like helical domains | Form a concave surface for protein-protein interactions |
| C-terminal transmembrane domain | Anchors FIS1 in the outer mitochondrial membrane |
| Cytoplasmic exposure | Bulk of protein faces cytosol for DRP1 recruitment |
| Associated Diseases | Aging, Als, Cardiomyopathy, Inflammation, Lymphoma |
| Known Drugs/Compounds | RAPAMYCIN |
| Interactions | AGING, AMPK, AND, APP, ATP, AUTOPHAGY |
| KG Connections | 362 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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