| Gene Symbol | CD40 |
| Full Name | Cluster of Differentiation 40 |
| Chromosome | 20q12 |
| Protein Family | TNF receptor superfamily |
| Function | CD40-CD40L signaling is central to immune function |
| Primary Expression | AD brain by microglia and astrocytes - CD40-CD40L interaction promotes: - Microglial activation - Pro-i |
| Molecular Weight | 48 kDa |
| Amino Acids | 277 aa |
| Exons | 9 |
| Pathways | NF-κB, MAPK pathway, PI3K |
| GeneCards | CD40 |
| Human Protein Atlas | CD40 |
| Associated Diseases | AD, ALI, Autoimmune, cancer, disease |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, AND, AQP4, CD8, C-FOS |
| KG Connections | 101 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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