gene 992 words KG: SNAP29
Contents

SNAP29 — Synaptosomal-Associated Protein 29

🧬 Gene Info
Gene SymbolSNAP29
Full NameSynaptosomal-Associated Protein 29
Functionis a member of the SNAP25 family of SNARE (Soluble N-ethylmaleimide-sensitive factor Attachment Protein Receptor) proteins[@snap2018][@snap2020].
Subcellular Localization</th><td>Cytoplasm, Plasma Membrane, Endosomes</td></tr>
Molecular Weight29 kDa
PathwaysNOTCH
GeneCardsSNAP29
Human Protein AtlasSNAP29
Associated DiseasesAging, Als, Ftd, Glioblastoma, Melanoma
Known Drugs/Compoundsrapamycin
InteractionsACAT1, ACTB, AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMPK
KG Connections708 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (14)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Autophagosome Maturation Checkpoint Control
Score: 0.71
Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.71
SASP-Mediated Complement Cascade Amplification
Score: 0.70
Extracellular Matrix Stiffness Modulation
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
Low Complexity Domain Cross-Linking Inhibition
Score: 0.62
Synaptic Vesicle Tau Capture Inhibition
Score: 0.58

Related Analyses (11)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (7)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
ACTB Gene
gene · KG edge: activates
AKT1 Gene
gene · KG edge: associated_with
AIM2 Inflammasome Modulation Therapy for Neurodegenerat
idea · KG edge: associated_with
Alzheimer Indonesia
institution · KG edge: regulates

Knowledge Graph (12 edges)

VAMP8 associated_with SNAP29
LAMP2 associated_with SNAP29
GBM associated_with SNAP29
LC3 associated_with SNAP29
STX17 associated_with SNAP29
SQSTM1 associated_with SNAP29
SNAP29 associated_with SDC1
OPTN associated_with SNAP29
ULK1 associated_with SNAP29
CALCOCO2 associated_with SNAP29

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