gene 845 words KG: SYN1
Contents

SYN1 Gene

🧬 Gene Info
Gene SymbolSYN1
ChromosomeXp11.23
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionPrimarily neuronal
PathwaysMAPK, mapk
Ensembl IDENSG00000102057
GeneCardsSYN1
Human Protein AtlasSYN1
Genomic Span~50 kb
Exon CountMultiple exons (13+)
Alternative SplicingProduces multiple isoforms (I, II, III)
Associated Diseasesaging, Als, Alzheimer, Alzheimer'S Disease
Known Drugs/Compoundsrapamycin, RAPAMYCIN
InteractionsACTB, Actin, AD, ADAM10, AKT, ALZHEIMER
KG Connections501 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (22)

Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.66
← Prevpg 2/2

Related Analyses (13)

Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · completed
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

See Also (13)

Astrocytes
cell · KG edge: activates
acetylcholine
general · KG edge: co_discussed
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: activates
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: activates

Knowledge Graph (12 edges)

ACTB activates SYN1
LAMP1 associated_with SYN1
MTOR associated_with SYN1
LC3 associated_with SYN1
TUBB3 associated_with SYN1
ATG7 activates SYN1
JUN activates SYN1
SQSTM1 associated_with SYN1
MAP2 associated_with SYN1
SYN1 associated_with CTSD

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