gene 1,811 words KG: RICTOR
Contents

RICTOR Gene

🧬 Gene Info
Gene SymbolRICTOR
Full NameRaptor Companion
Chromosome5p13.1
Functionencodes a critical component of the mechanistic target of rapamycin complex 2 (mTORC2), a key signaling hub that regulates cell survival, metabolism, cytoskeletal organization, and synaptic plastic...
Molecular Weight200 kDa
Amino Acids708 aa
PathwaysmTOR, mtor, mTOR signaling, MAPK
UniProt IDQ6R327
NCBI Gene ID253782
Ensembl IDENSG00000164327
OMIM610027
GeneCardsRICTOR
Human Protein AtlasRICTOR
Associated Diseasesneurodegeneration
Known Drugs/Compoundsrapamycin
InteractionsACETYL-COA, Actin, AKT, AKT1, AKT1S1, AMBRA1
KG Connections422 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Agent Input

Related Hypotheses (4)

CYP46A1 Overexpression Gene Therapy
Score: 0.98
APOE-Dependent Autophagy Restoration
Score: 0.88
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
VCP-Mediated Autophagy Enhancement
Score: 0.59

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40

See Also (10)

ATP P2X3 Receptor Neurons
cell · KG edge: interacts_with
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: interacts_with
Apoptosis in Neurodegeneration
entity · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: inhibits
AKT1 Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

ATF6 interacts_with RICTOR
OPTN interacts_with RICTOR
CASP3 interacts_with RICTOR
AKT1 interacts_with RICTOR
CALCOCO2 interacts_with RICTOR
CGAS interacts_with RICTOR
CFTR interacts_with RICTOR
SQSTM1 interacts_with RICTOR
RPS6KB1 interacts_with RICTOR
GRB2 interacts_with RICTOR

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