gene 682 words KG: RELB
Contents

RELB Gene

🧬 Gene Info
Gene SymbolRELB
Full NameRELB Proto-Oncogene, NF-Kappa-B Transcription Factor
Chromosome19q13.32
Protein FamilyNF-κB transcription factors
Protein TypeTranscription Factor
FunctionRELB is a NF-κB family member that primarily partners with p52 to form the non-canonical NF-κB pathway.
Primary Expressionglial cells and may have neuroprotective or inflammatory roles in the brain
Molecular Weight66 kDa
PathwaysNF-κB, NF-κB Pathway, NF-κB pathway, NF-κB signaling, NFKB
UniProt IDQ02880
NCBI Gene ID5971
Ensembl IDENSG00000100390
GeneCardsRELB
Human Protein AtlasRELB
Immune ResponseCritical for lymphocyte development and function
Associated DiseasesAls, Cancer, Carcinoma, Lung Cancer, Melanoma, Tumor
InteractionsCANCER, IGF1, INFLAMMATION, NF-ΚB, RPS6KB1, TNF
KG Connections95 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (9)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79
Competitive APOE4 Domain Stabilization Peptides
Score: 0.78
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

IL6 (Redirect)
redirect · KG edge: associated_with
nf-kb
general · KG edge: expressed_in
casp3
gene · KG edge: regulates
CCL3 Gene
gene · KG edge: regulates
CHRNA7 Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

PANX1 regulates RELB
S100B regulates RELB
RELB regulates P2RY1
RELB regulates CASP3
RELB regulates SOCS3
RELB regulates TRPA1
RELB regulates CXCL2
RELB regulates SNAP25
RELB regulates P2RX7
RELB regulates SYT2

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