| Gene Symbol | LEF1 |
| Chromosome | 4q25 |
| Protein Type | Transcription Factor |
| Function | is a transcription factor belonging to the T-cell factor/lymphoid enhancer-binding factor (TCF/LEF) family of DNA-binding proteins. |
| Primary Expression | multiple regions of the developing and adult brain, with particularly high expression in the hippocampal formation, cerebral [cortex](/brain-regions/c |
| Amino Acids | 399 aa |
| Pathways | Wnt, Wnt pathway, Wnt signaling |
| GeneCards | LEF1 |
| Human Protein Atlas | LEF1 |
| Associated Diseases | neurodegeneration |
| Interactions | AND, APOPTOSIS, BETA-CATENIN, CACNA1G, CAV3, CAV3.1 |
| KG Connections | 149 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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