| Gene Symbol | NCOA4 |
| Full Name | Nuclear Receptor Coactivator 4 |
| Chromosome | 10q11.23 |
| Protein Type | Receptor |
| Function | NCOA4 performs two major functions in the cell: |
| Primary Expression | human tissues: - Brain: Moderate expression in cortex, hippocampus, basal ganglia - Highe |
| Molecular Weight | 70 kDa |
| Pathways | Akt, Autophagy, FERRITINOPHAGY, Ferroptosis, Iron Metabolism |
| UniProt ID | Q9UBR1 |
| NCBI Gene ID | 8031 |
| Ensembl ID | ENSG00000135333 |
| OMIM | 605161 |
| GeneCards | NCOA4 |
| Human Protein Atlas | NCOA4 |
| Associated Diseases | Carcinoma, Cardiovascular, Hepatocellular Carcinoma, Lactation Dysfunction, Parkinson, Tumor |
| Known Drugs/Compounds | rapamycin, Salidroside |
| Interactions | ACETYL-COA, ACSL4, ACTB, AGER, ALOX, ALZHEIMER |
| SciDEX Hypotheses | FUS-ALS-Specific Ferroptosis Vulnerability Through |
| KG Connections | 453 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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