gene 866 words KG: MAP1B
Contents

MAP1B Gene

🧬 Gene Info
Gene SymbolMAP1B
Full NameMicrotubule Associated Protein 1B
AliasesMicrotubule-Associated Protein 1B
Chromosome5q13.2
Protein FamilyMAP1 family
Protein TypeProtein
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressiondeveloping neurons
Subcellular LocalizationAxons, growth cones, synaptic terminals, dendrites
Molecular Weight300 kDa
Amino Acids2700 aa
PathwaysAutophagy, NF-kB signaling
UniProt IDP46821
GeneCardsMAP1B
Human Protein AtlasMAP1B
Associated DiseasesAD, ALI, Als, AMI, NMO, RA
InteractionsAUTOPHAGY, LC3, MAP1A, MAP2, MAP6, Proteins
KG Connections60 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

Related Hypotheses (5)

Reelin-Mediated Cytoskeletal Stabilization Protocol
Score: 0.69
Tau-Independent Microtubule Stabilization via MAP6 Enhanceme
Score: 0.57
CYP46A1 Overexpression Gene Therapy
Score: 0.98
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Quantum Coherence Disruption in Cellular Communication
Score: 0.63

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (10)

blarcamesine-axon
clinical_trial · KG edge: transports
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
GABARAP Gene
gene · KG edge: regulates
HSP90AA1 Gene
gene · KG edge: associated_with
MAP1LC3A Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

MAP2 interacts_with MAP1B
MAP1B interacts_with MAP6
MAP1B interacts_with MAP2
MAP1B regulates GABARAP
MAP1B implicated_in NMO
MAP1B interacts_with UBIQUITIN
MAP1B associated_with NBR1
MAP1B interacts_with LC3
MAP1B interacts_with TAU
MAP6 interacts_with MAP1B

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...