gene 1,564 words KG: KDR
Contents

KDR Gene

🧬 Gene Info
Gene SymbolKDR
AliasesVEGFR2
Chromosome4q12
Protein TypeReceptor
Functionis a receptor tyrosine kinase that serves as the primary signaling receptor for VEGF-mediated angiogenesis and vascular development.
Molecular Weight230 kDa
Amino Acids356 aa
Exons30
PathwaysFunction
GeneCardsKDR
Human Protein AtlasKDR
Associated DiseasesAlzheimer's disease, Parkinson's disease
InteractionsAND, HDAC9, ICAM1, MMP2, MMP9, NANOG
KG Connections55 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (8)

APOE-Dependent Autophagy Restoration
Score: 0.89
CYP46A1 Overexpression Gene Therapy
Score: 0.77
Retinal Vascular Microcirculation Rescue
Score: 0.72
Endothelial Glycocalyx Regeneration via Syndecan-1 Upregulat
Score: 0.71
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Glial Glycocalyx Remodeling Therapy
Score: 0.65
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
Piezoelectric Nanochannel BBB Disruption
Score: 0.52

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Apoptosis in Neurodegeneration
entity · KG edge: therapeutic_target
CD44 - Cell Surface Glycoprotein
gene · KG edge: biomarker_for
EGF Gene
gene · KG edge: biomarker_for
FGF9 Gene
gene · KG edge: biomarker_for
HRAS (Harvey Rat Sarcoma Viral Oncogene Homolog)
gene · KG edge: associated_with

Knowledge Graph (12 edges)

RAGE therapeutic_target KDR
SERPINE1 inhibits KDR
NOS2 inhibits KDR
MMP2 inhibits KDR
PTGS2 inhibits KDR
KDR inhibits MMP9
KDR inhibits ICAM1
KDR inhibits SPP1
ICAM1 inhibits KDR
MMP9 inhibits KDR

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