gene 1,593 words KG: GNAL
Contents

GNAL — Gαolf Subunit

🧬 Gene Info
Gene SymbolGNAL
Full NameGαolf Subunit
Chromosome18p11.21
Functionencodes the Gαolf protein (Guanine nucleotide-binding protein subunit alpha L), a member of the Gαs family of heterotrimeric G proteins
Primary ExpressionNeuron-specific (olfactory epithelium, striatum)
Molecular Weight44 kDa
Exons12
UniProt ID[P38405](https://www.uniprot.org/uniprot/P38405)
Ensembl IDENSG00000141449
GeneCardsGNAL
Human Protein AtlasGNAL
Chromosomal location18p11.21
Genomic span~67 kb, 12 exons
Associated DiseasesAls
InteractionsCAMKII, CCND1, CYTOKINES, IL1B, IL3, IL8
KG Connections145 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (187)

Nucleolar Stress Response Normalization
Score: 0.65
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
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Mitochondrial Calcium Buffering Enhancement via MCU Modulati
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APOE-Mediated Synaptic Lipid Raft Stabilization
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Glial Glycocalyx Remodeling Therapy
Score: 0.65
DNMT1-Targeting Antisense Oligonucleotide Reset
Score: 0.65
HCN1-Mediated Resonance Frequency Stabilization Therapy
Score: 0.65
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
Score: 0.65
Synthetic Biology Rewiring via Orthogonal Receptors
Score: 0.65
Ephrin-B2/EphB4 Axis Manipulation
Score: 0.64
Glycine-Rich Domain Competitive Inhibition
Score: 0.64
Transglutaminase-2 Cross-Linking Inhibition Strategy
Score: 0.64
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
Multi-Modal CRISPR Platform for Simultaneous Editing and Mon
Score: 0.63
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62
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Related Analyses (30)

Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

See Also (15)

ATP P2X3 Receptor Neurons
cell · KG edge: co_discussed
Amyotrophic Lateral Sclerosis
redirect · KG edge: co_discussed
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: co_discussed
Apoptosis in Neurodegeneration
entity · KG edge: co_discussed
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: co_discussed

Knowledge Graph (12 edges)

GNAL expressed_in VAMP7
GNAL expressed_in MMP9
GNAL inhibits PI3K
GNAL associated_with AKT
GNAL associated_with AKT1
GNAL expressed_in MCC
GNAL expressed_in CXCR4
GNAL associated_with ALDH1A3
GCH1 associated_with GNAL
THAP1 associated_with GNAL

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