concept

SAT1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SAT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

61Connections

0Hypotheses

0Analyses

41Outgoing

20Incoming

0Experiments

0Debates

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💡 Concept Info

Name	SAT1
Key Genes/Proteins	ACO1, ALOX12, ALOX15, ALOX5, ALOXE3, AND
Related Diseases	Cancer, DLBCL
Related Pathways	Cell Cycle

Pathway Diagram

graph TD
    SAT1["SAT1"]
    SAT1 -->|"activates"| Cancer["Cancer"]
    SAT1 -->|"activates"| FER["FER"]
    SAT1 -->|"activates"| ALOX15["ALOX15"]
    SAT1 -->|"activates"| RNA["RNA"]
    SAT1 -->|"activates"| AND["AND"]
    SAT1 -->|"activates"| NFE2L2["NFE2L2"]
    SAT1 -->|"activates"| GENES["GENES"]
    SAT1 -->|"activates"| Ferroptosis["Ferroptosis"]
    SBFI26["SBFI26"] -->|"upregulates"| SAT1
    CANCER["CANCER"] -->|"activates"| SAT1
    HMOX1["HMOX1"] -->|"activates"| SAT1
    GSH["GSH"] -->|"activates"| SAT1
    CHAC1["CHAC1"] -->|"activates"| SAT1
    ALOXE3["ALOXE3"] -->|"activates"| SAT1
    ALOX12["ALOX12"] -->|"activates"| SAT1
    ALOX5["ALOX5"] -->|"activates"| SAT1

Outgoing (41)

Target	Relation	Type	Str
ferroptosis	promotes	process	0.80
DLBCL	biomarker_for	disease	0.80
Cancer	activates	disease	0.65
Ferroptosis	associated_with	disease	0.65
Lymphoma	associated_with	disease	0.65
NFE2L2	activates	gene	0.60
GENES	activates	gene	0.60
Ferroptosis	activates	pathway	0.60
ALOX12	activates	gene	0.60
ALOX5	activates	gene	0.60
FERROPTOSIS	activates	gene	0.60
HMOX1	activates	gene	0.60
CHAC1	activates	gene	0.60
ALOXE3	activates	gene	0.60
GSH	activates	gene	0.60
ATM	biomarker_for	gene	0.60
FER	activates	gene	0.60
FERROPTOSIS	associated_with	gene	0.60
RNA	associated_with	gene	0.60
BRD4	biomarker_for	gene	0.60
Oxidative Phosphorylation	associated_with	pathway	0.60
Mtor	biomarker_for	pathway	0.60
Immune Response	associated_with	pathway	0.60
Cell Cycle	associated_with	pathway	0.60
Ras	activates	protein	0.60
SRXN1	biomarker_for	gene	0.60
Fus	associated_with	protein	0.60
App	associated_with	protein	0.60
ferroptosis	activates	process	0.60
MTOR	biomarker_for	gene	0.60
ALOX15	activates	gene	0.60
RNA	activates	gene	0.60
AND	activates	gene	0.60
MTOR	therapeutic_target	gene	0.60
YBX1	regulates	gene	0.60
JUN	activates	gene	0.60
HERC5	regulates	gene	0.60
AUTOPHAGY	activates	gene	0.60
Ras	associated_with	protein	0.60
App	activates	protein	0.60
ferroptosis	participates_in	pathway	0.60

Incoming (20)

Source	Relation	Type	Str
SBFI26	upregulates	drug	0.85
ATM	biomarker_for	gene	0.60
BRD4	biomarker_for	gene	0.60
MTOR	biomarker_for	gene	0.60
PRDX1	biomarker_for	gene	0.60
SRXN1	biomarker_for	gene	0.60
CANCER	activates	gene	0.60
HMOX1	activates	gene	0.60
GSH	activates	gene	0.60
CHAC1	activates	gene	0.60
ALOXE3	activates	gene	0.60
ALOX12	activates	gene	0.60
ALOX5	activates	gene	0.60
FERROPTOSIS	activates	gene	0.60
ALOX15	activates	gene	0.60
NFE2L2	activates	gene	0.60
ACO1	biomarker_for	gene	0.60
LPIN1	biomarker_for	gene	0.60
MT1G	biomarker_for	gene	0.60
PEBP1	biomarker_for	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning SAT1 in their description or question text

No additional research found