concept

EPITHELIAL

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about EPITHELIAL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

655Connections

0Hypotheses

0Analyses

4Outgoing

50Incoming

0Experiments

0Debates

No summary available yet.

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💡 Concept Info

Name	EPITHELIAL

Pathway Diagram

graph TD
    EPITHELIAL["EPITHELIAL"]
    style EPITHELIAL fill:#1a237e,stroke:#4fc3f7,stroke-width:3px
    EPITHELIAL -->|"expressed in"| Basal_Ganglia((Basal Ganglia))
    EPITHELIAL -->|"expressed in"| Gray_Matter((Gray Matter))
    EPITHELIAL -->|"expressed in"| Brainstem((Brainstem))
    EPITHELIAL -->|"expressed in"| Substantia_Nigra((Substantia Nigra))
    CPT1A([CPT1A]) -->|"regulates"| EPITHELIAL
    MITOCHONDRIA([MITOCHONDRIA]) -->|"activates"| EPITHELIAL
    SQSTM1([SQSTM1]) -->|"regulates"| EPITHELIAL
    PPARG([PPARG]) -->|"regulates"| EPITHELIAL
    RPS6KB1([RPS6KB1]) -->|"regulates"| EPITHELIAL
    LRP2([LRP2]) -->|"regulates"| EPITHELIAL
    NADH([NADH]) -->|"regulates"| EPITHELIAL
    ATG([ATG]) -->|"regulates"| EPITHELIAL
    PPARA([PPARA]) -->|"regulates"| EPITHELIAL
    EIF4EBP1([EIF4EBP1]) -->|"regulates"| EPITHELIAL

Outgoing (4)

Target	Relation	Type	Str
Basal Ganglia	expressed_in	brain_region	0.50
Gray Matter	expressed_in	brain_region	0.50
Substantia Nigra	expressed_in	brain_region	0.50
Brainstem	expressed_in	brain_region	0.50

Incoming (651)

Source	Relation	Type	Str
EMP1	regulates	gene	0.60
TP53	associated_with	gene	0.60
AQP4	expressed_in	gene	0.60
TCR	expressed_in	gene	0.60
APOPTOSIS	inhibits	gene	0.60
RNA	inhibits	gene	0.60
APOPTOSIS	therapeutic_target	gene	0.60
UNC5B	activates	gene	0.60
RNA	regulates	gene	0.60
PRMT1	therapeutic_target	gene	0.60
AUTOPHAGY	therapeutic_target	gene	0.60
PRMT5	therapeutic_target	gene	0.60
DNA	therapeutic_target	gene	0.60
MTORC1	associated_with	gene	0.60
LYSOSOME	regulates	gene	0.60
LAMP1	associated_with	gene	0.60
AUTOPHAGY	associated_with	gene	0.60
MCOLN1	associated_with	gene	0.60
STX17	associated_with	gene	0.60
ATG12	associated_with	gene	0.60
GAPDH	associated_with	gene	0.60
NSF	associated_with	gene	0.60
ULK1	associated_with	gene	0.60
VAMP8	associated_with	gene	0.60
TREK-1	activates	gene	0.60
IL-6	activates	gene	0.60
MITOPHAGY	activates	gene	0.60
ATP	activates	gene	0.60
AUTOPHAGY	activates	gene	0.60
MTDNA	activates	gene	0.60
DNA	activates	gene	0.60
SIRT3	activates	gene	0.60
EGFR	activates	gene	0.60
TFAM	activates	gene	0.60
TAZ	regulates	gene	0.60
LATS1	regulates	gene	0.60
HIPPO	regulates	gene	0.60
YAP	regulates	gene	0.60
AMPK	protects_against	gene	0.60
SIRT1	protects_against	gene	0.60
AUTOPHAGY	protects_against	gene	0.60
FOXO3	protects_against	gene	0.60
LC3B	protects_against	gene	0.60
OCLN	interacts_with	gene	0.60
AMPK	activates	gene	0.60
PARKIN	activates	gene	0.60
MITOPHAGY	causes	gene	0.60
MTOR	causes	gene	0.60
MITOCHONDRIA	causes	gene	0.60
CERS2	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning EPITHELIAL in their description or question text

No additional research found