Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CAUDATE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No summary available yet.
No AI portrait yet
| Name | CAUDATE |
| Related Diseases | ALZHEIMER, ALZHEIMER'S, ALZHEIMER'S DISEASE |
graph TD
CAUDATE["CAUDATE"]
AGING["AGING"] -->|"regulates"| CAUDATE
RORB["RORB"] -->|"expressed in"| CAUDATE
TMEM106B["TMEM106B"] -->|"expressed in"| CAUDATE
TAU["TAU"] -->|"expressed in"| CAUDATE
NEURON["NEURON"] -->|"expressed in"| CAUDATE
PVALB["PVALB"] -->|"expressed in"| CAUDATE
ALZHEIMER["ALZHEIMER"] -->|"expressed in"| CAUDATE| Target | Relation | Type | Str |
|---|---|---|---|
| PUTAMEN | co_discussed | brain_region | 0.40 |
| THALAMUS | co_discussed | brain_region | 0.40 |
| WHITE MATTER | co_discussed | brain_region | 0.40 |
| CORTEX | co_discussed | brain_region | 0.40 |
| FRONTAL | co_discussed | brain_region | 0.40 |
| NEURON | co_discussed | cell_type | 0.40 |
| PREFRONTAL | co_discussed | brain_region | 0.40 |
| Source | Relation | Type | Str |
|---|---|---|---|
| AGING | expressed_in | gene | 0.55 |
| NEURON | expressed_in | gene | 0.55 |
| ALZHEIMER | expressed_in | gene | 0.55 |
| Aging | associated_with | disease | 0.55 |
| Alzheimer | associated_with | disease | 0.55 |
| ASTROCYTES | expressed_in | gene | 0.55 |
| MICROGLIA | expressed_in | gene | 0.55 |
| Als | associated_with | disease | 0.55 |
| RORB | expressed_in | gene | 0.55 |
| TMEM106B | expressed_in | gene | 0.55 |
| TAU | expressed_in | gene | 0.55 |
| PVALB | expressed_in | gene | 0.55 |
| FLT1 | expressed_in | gene | 0.55 |
| UBIQUITIN | expressed_in | gene | 0.55 |
| TNF | expressed_in | gene | 0.55 |
| PLCG2 | expressed_in | gene | 0.55 |
| NFE2L2 | expressed_in | gene | 0.55 |
| NRF2 | expressed_in | gene | 0.55 |
| HBA1 | expressed_in | gene | 0.55 |
| FUS | expressed_in | gene | 0.55 |
| TDP-43 | expressed_in | gene | 0.55 |
| RNA | expressed_in | gene | 0.55 |
| PARKINSON | expressed_in | gene | 0.55 |
| Neuroinflammation | associated_with | disease | 0.55 |
| Parkinson | associated_with | disease | 0.55 |
| AMYLOID | expressed_in | gene | 0.55 |
| Neurodegeneration | associated_with | disease | 0.55 |
| Interneuron | expressed_in | cell_type | 0.50 |
| Oligodendrocyte | expressed_in | cell_type | 0.50 |
| Astrocyte | expressed_in | cell_type | 0.50 |
| BRAINSTEM | co_discussed | brain_region | 0.40 |
| ALZHEIMER | co_discussed | disease | 0.40 |
| ALZHEIMER'S | co_discussed | disease | 0.40 |
| ALZHEIMER'S DISEASE | co_discussed | disease | 0.40 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning CAUDATE in their description or question text
No additional research found