gene

CAV3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CAV3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

67Connections

0Hypotheses

0Analyses

50Outgoing

13Incoming

0Experiments

0Debates

Summary

Caveolin 3 - muscle-specific caveolin essential for skeletal muscle function and neuromuscular junctions

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🧬 Gene Info

Gene Symbol	CAV3
Aliases	Caveolin 3
Function	Cav3 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Primary Expression	Thalamus, Hippocampus
Molecular Weight	18 kDa
Pathways	Amyloid, Complement, Wnt
GeneCards	CAV3
Human Protein Atlas	CAV3
Associated Diseases	Ataxia, Autism, Epilepsy, Spinocerebellar Ataxia
Interactions	AGING, ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, Amyloid Beta, BETA-CATENIN
KG Connections	67 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CAV3

gene · 960 words

→

CAV3 Protein

protein · 604 words

→

Pathway Diagram

graph TD
    CAV3["CAV3"]
    ALS{"ALS"}
    CAV3 -->|"inhibits"| ALS
    Alzheimer{"Alzheimer"}
    CAV3 -->|"inhibits"| Alzheimer
    Aging{"Aging"}
    CAV3 -->|"inhibits"| Aging
    AMYLOID["AMYLOID"]
    CAV3 -->|"inhibits"| AMYLOID
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    CAV3 -->|"inhibits"| ALZHEIMER_S_DISEASE
    ALZHEIMER["ALZHEIMER"]
    CAV3 -->|"inhibits"| ALZHEIMER
    AGING["AGING"]
    CAV3 -->|"inhibits"| AGING
    Amyloid(["Amyloid"])
    CAV3 -->|"inhibits"| Amyloid
    Complement(["Complement"])
    CAV3 -->|"inhibits"| Complement
    AND["AND"]
    CAV3 -->|"inhibits"| AND
    neurodegeneration["neurodegeneration"]
    CAV3 -->|"implicated in"| neurodegeneration
    ALZHEIMER_S_DISEASE -->|"inhibits"| CAV3
    ALZHEIMER -->|"inhibits"| CAV3
    style CAV3 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0

Outgoing (54)

Target	Relation	Type	Str
Autism	associated_with	disease	0.65
Epilepsy	associated_with	disease	0.65
Als	inhibits	disease	0.65
Ataxia	associated_with	disease	0.65
Spinocerebellar Ataxia	associated_with	disease	0.65
ALS	inhibits	disease	0.65
Aging	inhibits	disease	0.65
Alzheimer	inhibits	disease	0.65
WNT3A	activates	gene	0.60
Purkinje	associated_with	cell_type	0.60
Rb	activates	protein	0.60
AMYLOID	inhibits	gene	0.60
ALZHEIMER'S DISEASE	inhibits	gene	0.60
ALZHEIMER	inhibits	gene	0.60
AGING	inhibits	gene	0.60
Complement	inhibits	pathway	0.60
CACNA1G	associated_with	gene	0.60
LEF1	regulates	gene	0.60
Amyloid	inhibits	pathway	0.60
GAIN	associated_with	gene	0.60
RNA	inhibits	gene	0.60
Wnt	activates	pathway	0.60
Neuron	activates	cell_type	0.60
EPILEPSY	associated_with	gene	0.60
Neuron	associated_with	cell_type	0.60
Amyloid Beta	inhibits	protein	0.60
Rb	inhibits	protein	0.60
Ras	activates	protein	0.60
Ras	associated_with	protein	0.60
Thalamus	expressed_in	brain_region	0.55
Hippocampus	expressed_in	brain_region	0.55
Neuron	expressed_in	cell_type	0.55
NEURONS	expressed_in	concept	0.50
CACNA1G	interacts_with	protein	0.50
LEF1	interacts_with	gene	0.50
GAIN	activates	gene	0.50
CAV3.1	interacts_with	protein	0.50
CAV3.1	activates	protein	0.50
CAV3.1	associated_with	protein	0.50
NEURONS	interacts_with	concept	0.50
THALAMUS	interacts_with	concept	0.50
BETA-CATENIN	interacts_with	protein	0.50
AMYLOID BETA	inhibits	concept	0.50
Alzheimer'S Disease	inhibits	disease	0.50
disease	inhibits	disease	0.50
ALZHEIMER'S	inhibits	concept	0.50
CAV3.1	expressed_in	protein	0.50
CAV3.1	inhibits	protein	0.50
aging	expressed_in	phenotype	0.50
Alzheimer'S Disease	expressed_in	disease	0.50

Incoming (13)

Source	Relation	Type	Str
AGING	inhibits	gene	0.60
AMYLOID	inhibits	gene	0.60
TRPC3	activates	gene	0.60
CAV1	activates	gene	0.60
GAIN	associated_with	gene	0.60
LEF1	regulates	gene	0.60
GENES	activates	gene	0.60
EPILEPSY	associated_with	gene	0.60
CACNA1G	encodes	gene	0.60
CACNA1G	associated_with	gene	0.60
ALZHEIMER'S DISEASE	inhibits	gene	0.60
ALZHEIMER	inhibits	gene	0.60
RNA	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CAV3 in their description or question text

No additional research found