protein

BETA-CATENIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BETA-CATENIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

29Connections

0Hypotheses

0Analyses

12Outgoing

17Incoming

0Experiments

0Debates

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🔬 Protein Info

Gene Symbol	BETA
Full Name	CATENIN
Protein Family	Beta-catenin family, Armadillo repeat proteins
Function	of 781 amino acids that is expressed in virtually all tissues, with particularly high expression in the brain
Subcellular Localization	Cytoplasm, nucleus, cell junctions
Molecular Weight	85 kDa
Amino Acids	781 aa
Pathways	Wnt signaling, Wnt
UniProt ID	P35222
GeneCards	BETA
Human Protein Atlas	BETA
Interactions	C1QBP, CACNA1G, CAV3, CAV3.1, LEF1, MTCL1
KG Connections	22 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: BETA-CATENIN — AlphaFold P35222 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

Beta-Catenin Protein

protein · 2111 words

→

Pathway Diagram

graph TD
    BETA_CATENIN["BETA-CATENIN"]
    CARCINOMA{"CARCINOMA"}
    BETA_CATENIN -->|"activates"| CARCINOMA
    NEURONS["NEURONS"]
    BETA_CATENIN -->|"interacts_with"| NEURONS
    Genes["Genes"]
    BETA_CATENIN -->|"activates"| Genes
    Differentiation["Differentiation"]
    BETA_CATENIN -->|"activates"| Differentiation
    MTCL1(["MTCL1"])
    MTCL1 -->|"activates"| BETA_CATENIN
    UBIQUITIN(["UBIQUITIN"])
    UBIQUITIN -->|"activates"| BETA_CATENIN
    CAV3(["CAV3"])
    CAV3 -->|"interacts_with"| BETA_CATENIN
    LEF1(["LEF1"])
    LEF1 -->|"interacts_with"| BETA_CATENIN
    style BETA_CATENIN fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#4fc3f7

Outgoing (12)

Target	Relation	Type	Str
Parkinson's disease	downregulates	disease	0.80
MELANOMA	downregulates	disease	0.80
beta-catenin_pathway	participates_in	pathway	0.72
CACNA1G	activates	gene	0.60
CARCINOMA	activates	disease	0.50
NEURONS	interacts_with	concept	0.50
NEURONS	associated_with	concept	0.50
THALAMUS	associated_with	concept	0.50
THALAMUS	interacts_with	concept	0.50
NEURONS	activates	concept	0.50
THALAMUS	activates	concept	0.50
Hippocampus	activates	entity	0.50

Incoming (17)

Source	Relation	Type	Str
Wnt	regulates	pathway	0.90
C1QBP	activates	protein	0.80
circMTCL1	activates	protein	0.72
CTNNB1	encodes	gene	0.72
CDH1	regulates	gene	0.70
PSEN2	regulates	gene	0.60
CACNA1G	interacts_with	protein	0.50
LEF1	activates	gene	0.50
LEF1	associated_with	gene	0.50
MTCL1	activates	gene	0.50
CACNA1G	activates	protein	0.50
PRESENILIN	regulates	protein	0.50
WNT3A	activates	gene	0.50
UBIQUITIN	activates	protein	0.50
CAV3	interacts_with	gene	0.50
LEF1	interacts_with	gene	0.50
CAV3.1	interacts_with	protein	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity