concept

ARTHRITIS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ARTHRITIS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

37Connections

0Hypotheses

0Analyses

7Outgoing

30Incoming

0Experiments

0Debates

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💡 Concept Info

Name	ARTHRITIS

Pathway Diagram

graph TD
    ARTHRITIS["ARTHRITIS"]
    ARTHRITIS -->|"activates"| Angiogenesis["Angiogenesis"]
    ARTHRITIS -->|"regulates"| Oxidative_Stress["Oxidative Stress"]
    ARTHRITIS -->|"inhibits"| Ferroptosis["Ferroptosis"]
    ARTHRITIS -->|"activates"| Mtor["Mtor"]
    FUT8["FUT8"] -->|"activates"| ARTHRITIS
    ST6GAL1["ST6GAL1"] -->|"activates"| ARTHRITIS
    ANGPT1["ANGPT1"] -->|"activates"| ARTHRITIS
    BMP2["BMP2"] -->|"activates"| ARTHRITIS
    FGF2["FGF2"] -->|"activates"| ARTHRITIS
    PDGFRB["PDGFRB"] -->|"activates"| ARTHRITIS
    RUNX2["RUNX2"] -->|"activates"| ARTHRITIS
    VEGF["VEGF"] -->|"activates"| ARTHRITIS

Outgoing (7)

Target	Relation	Type	Str
Angiogenesis	activates	pathway	0.55
Oxidative Stress	regulates	pathway	0.55
Ferroptosis	inhibits	pathway	0.55
Ferroptosis	activates	pathway	0.55
Apoptosis	associated_with	pathway	0.55
Autophagy	associated_with	pathway	0.55
Mtor	activates	pathway	0.55

Incoming (30)

Source	Relation	Type	Str
RLN	associated_with	protein	0.75
TERT	regulates	gene	0.65
CD14	regulates	gene	0.65
GPX4	inhibits	gene	0.65
SLC7A11	inhibits	gene	0.65
FER	activates	gene	0.65
GPX4	activates	gene	0.65
MMP1	inhibits	gene	0.65
MMP3	inhibits	gene	0.65
SLC7A11	activates	gene	0.65
SOX9	inhibits	gene	0.65
ATF6	activates	gene	0.65
EIF2AK3	activates	gene	0.65
ERN1	activates	gene	0.65
HSPA5	activates	gene	0.65
CD8	associated_with	gene	0.65
OVERVIEW	associated_with	gene	0.65
STING	associated_with	gene	0.65
STING1	associated_with	gene	0.65
GJA1	regulates	gene	0.65
P53	inhibits	gene	0.65
RUNX2	activates	gene	0.65
FUT8	activates	gene	0.65
ST6GAL1	activates	gene	0.65
ANGPT1	activates	gene	0.65
BMP2	activates	gene	0.65
FGF2	activates	gene	0.65
PDGFRB	activates	gene	0.65
VEGF	activates	gene	0.65
VEGFB	activates	gene	0.65

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ARTHRITIS in their description or question text

No additional research found