gene

ARID1A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ARID1A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

188Connections

0Hypotheses

0Analyses

50Outgoing

30Incoming

0Experiments

0Debates

No summary available yet.

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🧬 Gene Info

Gene Symbol	ARID1A
Chromosome	1p36.11
Function	BAF chromatin remodeling complex subunit
Exons	20
Pathways	Apoptosis, Dna Repair, Epigenetic, Immunotherapy, Mtor
Ensembl ID	ENSG00000117713
GeneCards	ARID1A
Human Protein Atlas	ARID1A
Associated Diseases	Als, Breast Cancer, Cancer, Carcinoma
Interactions	AND, APOPTOSIS, ATR, CACNA1G, CANCER, CD8
KG Connections	188 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    ARID1A["ARID1A"] -->|"associated"| Tumor["Tumor"]
    style Tumor fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    ARID1A["ARID1A"] -->|"associated"| Cancer["Cancer"]
    style Cancer fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    ARID1A["ARID1A"] -->|"upstream of"| cytosolic_ssDNA["cytosolic ssDNA"]
    style cytosolic_ssDNA fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    ARID1A["ARID1A"] -->|"associated"| KRAS["KRAS"]
    style KRAS fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    ARID1A["ARID1A"] -->|"associated"| GENES["GENES"]
    style GENES fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    ARID1A["ARID1A"] -->|"associated"| Ovarian_Cancer["Ovarian Cancer"]
    style Ovarian_Cancer fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    ARID1A["ARID1A"] -->|"associated"| Als["Als"]
    style Als fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    PTEN["PTEN"] -->|"associated"| ARID1A["ARID1A"]
    style PTEN fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    PIK3CA["PIK3CA"] -->|"associated"| ARID1A["ARID1A"]
    style PIK3CA fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    TP53["TP53"] -->|"associated"| ARID1A["ARID1A"]
    style TP53 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    FBXW7["FBXW7"] -->|"associated"| ARID1A["ARID1A"]
    style FBXW7 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    CANCER["CANCER"] -->|"therapeutic target"| ARID1A["ARID1A"]
    style CANCER fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    style ARID1A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (158)

Target	Relation	Type	Str
Tumor	associated_with	disease	1.00
Cancer	associated_with	disease	0.95
cytosolic ssDNA	upstream_of	phenotype	0.95
CANCER	associated_with	gene	0.90
Tumor	activates	disease	0.85
Cancer	activates	disease	0.85
GENES	associated_with	gene	0.80
KRAS	associated_with	gene	0.80
Ovarian Cancer	associated_with	disease	0.75
Als	associated_with	disease	0.75
Tumor	expressed_in	disease	0.75
Cancer	expressed_in	disease	0.75
Cancer	regulates	disease	0.75
CTNNB1	associated_with	gene	0.70
DNA	regulates	gene	0.70
Immune Checkpoint	inhibits	pathway	0.70
CANCER	causes	disease	0.70
PIK3CA	associated_with	gene	0.70
TP53	associated_with	gene	0.70
PI3K	expressed_in	gene	0.70
DNA	associated_with	gene	0.70
Epigenetic	regulates	pathway	0.70
Hepatocellular Carcinoma	risk_factor_for	disease	0.68
Colorectal Cancer	associated_with	disease	0.65
Gastric Cancer	associated_with	disease	0.65
Carcinoma	activates	disease	0.65
Ms	activates	disease	0.65
Gastric Cancer	inhibits	disease	0.65
Necroptosis	expressed_in	disease	0.65
Cancer	treats	disease	0.65
Als	treats	disease	0.65
Tumor	inhibits	disease	0.65
Prostate Cancer	activates	disease	0.65
Inflammation	activates	disease	0.65
Als	regulates	disease	0.65
Colorectal Cancer	expressed_in	disease	0.65
Renal Cell Carcinoma	contributes_to	disease	0.65
Als	expressed_in	disease	0.65
Fibrosis	expressed_in	disease	0.65
Als	inhibits	disease	0.65
Aging	activates	disease	0.65
Pancreatic Cancer	associated_with	disease	0.65
BREAST CANCER	sensitizes_to	disease	0.65
BREAST CANCER	causes	disease	0.65
Breast Cancer	associated_with	disease	0.65
Inflammation	associated_with	disease	0.65
Carcinoma	associated_with	disease	0.65
Cancer	encodes	disease	0.65
Aging	encodes	disease	0.65
Carcinoma	therapeutic_target	disease	0.65

Incoming (30)

Source	Relation	Type	Str
PTEN	associated_with	gene	0.90
FGFR3	associated_with	gene	0.60
CDKN2A	encodes	gene	0.60
PIK3CA	associated_with	gene	0.60
TP53	associated_with	gene	0.60
BAX	regulates	gene	0.60
BRAF	associated_with	gene	0.60
TGFBR2	regulates	gene	0.60
KRAS	activates	gene	0.60
APOPTOSIS	inhibits	gene	0.60
CANCER	expressed_in	gene	0.60
APOPTOSIS	regulates	gene	0.60
CANCER	regulates	gene	0.60
GENES	interacts_with	gene	0.60
SMARCA4	interacts_with	gene	0.60
ASH1L	contributes_to	gene	0.60
APC	associated_with	gene	0.60
PMS2	activates	gene	0.60
CACNA1G	activates	gene	0.60
DNA	associated_with	gene	0.60
ALK	associated_with	gene	0.60
CD8	activates	gene	0.60
CDKN2A	activates	gene	0.60
MLH1	activates	gene	0.60
NEUROG1	activates	gene	0.60
FBXW7	associated_with	gene	0.60
CANCER	therapeutic_target	gene	0.60
P53	activates	gene	0.60
CANCER	activates	gene	0.60
ATEZOLIZUMAB	associated_with	drug	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ARID1A in their description or question text

No additional research found

ARID1A

Understanding Entity Pages

Wiki Pages (3)

ARID1A

ARID1A Protein

KDM5A Protein (Lysine Specific Demethylase 5A (JARID1A))

Pathway Diagram

Outgoing (158)

Incoming (30)

Targeting Hypotheses (0)

Mentioning Analyses (0)

Experiments (0)

Related Papers (0)

Debates (0)

Related Research