gene 645 words KG: UVRAG
Contents

UVRAG Gene

🧬 Gene Info
Gene SymbolUVRAG
Full NameUV Radiation Resistance Associated Gene
Chromosome11q13.4
FunctionIt functions as a positive regulator of autophagy through multiple mechanisms
Molecular Weight89 kDa
Amino Acids783 aa
Exons20
PathwaysPI3K
UniProt ID[Q9P2K6](https://www.uniprot.org/uniprot/Q9P2K6)
Ensembl IDENSG00000136531
GeneCardsUVRAG
Human Protein AtlasUVRAG
Associated DiseasesALS, Cancer, Cardiovascular, dementia, frontotemporal, Inflammation
Known Drugs/Compoundsrapamycin
InteractionsACTB, AKT, AMBRA1, AMPK, AMYLOID, AND
KG Connections350 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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Knowledge Graph

Related Hypotheses (9)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
APOE-Dependent Autophagy Restoration
Score: 0.85
Senescent Microglia Resolution via Maresins-Senolytics Combi
Score: 0.78
Astroglial Gap Junction Coordination via Connexin-43 Phospho
Score: 0.72
Autophagosome Maturation Checkpoint Control
Score: 0.71

Related Analyses (4)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (9)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: associated_with
ACTB Gene
gene · KG edge: regulates
AMBRA1 Gene
gene · KG edge: activates
ar
gene · KG edge: activates

Knowledge Graph (12 edges)

ACTB regulates UVRAG
CDC42 regulates UVRAG
CASP3 regulates UVRAG
SQSTM1 associated_with UVRAG
TUBB3 associated_with UVRAG
STK11 associated_with UVRAG
VIM associated_with UVRAG
BECN1 regulates UVRAG
HDAC6 associated_with UVRAG
GAPDH regulates UVRAG

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