| Gene Symbol | TXN |
| Full Name | Thioredoxin |
| Chromosome | 9q31.3 |
| Protein Type | Gene |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | reactive astrocytes - Oligodendrocytes: Important for myelin maintenance - Microglia: Upregulated i |
| Molecular Weight | 12 kDa |
| Pathways | NF-κB |
| UniProt ID | P10599 |
| NCBI Gene ID | 7295 |
| Ensembl ID | ENSG00000136810 |
| GeneCards | TXN |
| Human Protein Atlas | TXN |
| Active Site | Cys-Gly-Pro-Cys motif mediates redox reactions |
| Reducing Power | Uses NADPH via TXNRD to maintain reduced state |
| Associated Diseases | ALS, Alzheimer |
| Interactions | AGING, ALZHEIMER, ALZHEIMER'S DISEASE, AMBRA1, AND, ATM |
| KG Connections | 129 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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