gene 2,479 words KG: SLC2A1
Contents

SLC2A1 Gene

🧬 Gene Info
Gene SymbolSLC2A1
Full NameGlucose Transporter 1 (GLUT1)
Chromosome1p34.2
Protein TypeTransporter
Functionis a facilitative glucose transporter belonging to the SLC2A family that provides the critical link between systemic glucose supply and cerebral energy metabolism.
Molecular Weight54 kDa
Amino Acids492 aa
Exons10
PathwaysFerroptosis, Mapk, Oxidative Stress, autophagy pathway, unfolded protein response
UniProt IDP11166
NCBI Gene ID6513
Ensembl IDENSG00000117394
OMIM138140
GeneCardsSLC2A1
Human Protein AtlasSLC2A1
Associated DiseasesAls, Ataxia, Cancer, Carcinoma, Infection, Ms
InteractionsABCB1, ABCG2, AGING, AKT1, ALZHEIMER, ALZHEIMER'S DISEASE
SciDEX HypothesesGLUT1-Mediated Glucose Flux Coefficient as Neuropr
KG Connections237 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (13)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.81
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.74
Metabolic Switch Targeting for A1→A2 Repolarization
Score: 0.73

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: inhibits
AKT1 Gene
gene · KG edge: interacts_with
ATM Gene
gene · KG edge: associated_with
ATR Gene
gene · KG edge: associated_with

Knowledge Graph (12 edges)

RB1 inhibits SLC2A1
PIK3CA interacts_with SLC2A1
MMP9 interacts_with SLC2A1
PPARA interacts_with SLC2A1
IGF1R interacts_with SLC2A1
RELA interacts_with SLC2A1
AKT1 interacts_with SLC2A1
TTR interacts_with SLC2A1
PPARG interacts_with SLC2A1
ESR1 interacts_with SLC2A1

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