Contents

PIK3C3 (VPS34) Protein

🔬 Protein Info

Gene Symbol	PIK3C3
Aliases	VPS34
Chromosome	18q12.3
Protein Family	Class III Phosphoinositide 3-kinase (PI3K3C)
Function	PIK3C3 contributes to lysosomal biogenesis and function through its role in autophagosome-lysosome fusion. The protein interacts with the HOPS complex via VPS34-generated PI3P
Subcellular Localization	Cytosol, endosomal membrane, phagophore
Molecular Weight	100 kDa
Amino Acids	887 aa
Exons	32
Pathways	PI3K
UniProt ID	Q8N3F7
Ensembl ID	ENSG00000055070
GeneCards	PIK3C3
Human Protein Atlas	PIK3C3
Associated Diseases	AD, ADH, Als, Alzheimer, AMI
Known Drugs/Compounds	rapamycin
Interactions	ACAT1, ACETYL-COA, AKT, AKT1, AKT1S1, ALZHEIMER
KG Connections	1112 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING