gene 524 words KG: TGFBR1
Contents

TGFBR1 — TGF-beta Receptor 1

🧬 Gene Info
Gene SymbolTGFBR1
Full NameTGF-beta Receptor 1
Chromosome9q22
Protein TypeReceptor
FunctionTGFBR1 encodes the Type I TGF-beta receptor, a serine/threonine protein kinase that mediates the signaling of transforming growth factor-beta (TGF-β) family cytokines.
Amino Acids567 aa
PathwaysTGF-β, TGF-β signaling
UniProt IDP36897
NCBI Gene ID7046
Ensembl IDENSG00000106799
OMIM190181
GeneCardsTGFBR1
Human Protein AtlasTGFBR1
Extracellular domainLigand binding
Transmembrane domainSingle pass
Associated DiseasesAls, Cancer, Carcinoma, epilepsy, Ms, Tumor
InteractionsACVR1, AKT, AND, BMP4, BMP7, CBL
SciDEX HypothesesEarly Postnatal TGF-beta Signaling Establishes Lif
KG Connections95 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (5)

Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.84
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Ocular Immune Privilege Extension
Score: 0.69
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67

Related Analyses (5)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

ACVR1 Gene
gene · KG edge: interacts_with
BMP2 — Bone Morphogenetic Protein 2
gene · KG edge: associated_with
BMP4 Gene (Bone Morphogenetic Protein 4)
gene · KG edge: activates
BMP7 Gene (Bone Morphogenetic Protein 7)
gene · KG edge: activates
CBL Gene
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

TGFBR2 associated_with TGFBR1
BMP4 activates TGFBR1
MYC associated_with TGFBR1
E2F5 associated_with TGFBR1
CDKN2B associated_with TGFBR1
TGFBR1 associated_with BMP2
TGFBR1 activates TGFB2
TGFBR1 activates BMP7
PIK3CA associated_with TGFBR1
CDK6 associated_with TGFBR1

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