gene 987 words KG: GAL
Contents

GAL Gene

🧬 Gene Info
Gene SymbolGAL
Chromosome11q13.2
FunctionThe GAL gene encodes preprogalanin, which is processed to galanin (1-29) and galanin message-associated peptide (GMAP).
Amino Acids30 aa
PathwaysApoptosis, Hippo Pathway
Ensembl IDENSG00000178394
GeneCardsGAL
Human Protein AtlasGAL
Associated DiseasesAging, Alzheimer, Cancer, Ms, Rheumatoid Arthritis, Senescence
InteractionsAGING, AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AMPK, AMYLOID
KG Connections287 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (11)

APOE-Dependent Autophagy Restoration
Score: 0.88
Circadian Clock-Autophagy Synchronization
Score: 0.76
Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
CYP46A1 Overexpression Gene Therapy
Score: 0.73
Circadian Rhythm Entrainment of Reactive Astrocytes
Score: 0.72
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
TREM2-mediated microglial tau clearance enhancement
Score: 0.62
Temporal Decoupling via Circadian Clock Reset
Score: 0.54

Related Analyses (6)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Synaptic pruning by microglia in early AD
neurodegeneration · archived

See Also (13)

Astrocytes
cell · KG edge: inhibits
ATP P2X3 Receptor Neurons
cell · KG edge: activates
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: associated_with
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activates

Knowledge Graph (12 edges)

GAL activates PI3K
GAL activates NRF2
GAL activates AKT
GAL activates TLR4
GAL activates TREM2
GAL activates NLRP3
GAL regulates TAZ
GAL regulates CLOCK
GAL associated_with BMAL1
GAL regulates ARNT

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