gene 990 words KG: TGFB2
Contents

TGFB2 Gene

🧬 Gene Info
Gene SymbolTGFB2
Full NameTransforming Growth Factor Beta 2
Chromosome1q41
Functionis a member of the TGF-beta superfamily of cytokines that plays critical roles in neural development, synaptic plasticity, and neuroinflammation regulation[@massague2012][@krieglstein2012].
Molecular Weight47.7 kDa
Amino Acids414 aa
Exons7
PathwaysTGF-β
UniProt IDP08123
NCBI Gene ID7048
Ensembl IDENSG00000192958
OMIM190220
GeneCardsTGFB2
Human Protein AtlasTGFB2
Associated DiseasesCancer, Carcinoma, Ms, Tumor
InteractionsAND, BMP4, BMP7, TGFBR1
KG Connections31 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (2)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (14)

Neurodegeneration
disease · KG edge: implicated_in
Genes
index · KG edge: associated_with
BMP2 — Bone Morphogenetic Protein 2
gene · KG edge: associated_with
BMP4 Gene (Bone Morphogenetic Protein 4)
gene · KG edge: activates
BMP7 Gene (Bone Morphogenetic Protein 7)
gene · KG edge: activates

Knowledge Graph (12 edges)

TGFBR2 associated_with TGFB2
BMP4 activates TGFB2
MYC associated_with TGFB2
E2F5 associated_with TGFB2
CDKN2B associated_with TGFB2
TGFBR1 activates TGFB2
BMP2 associated_with TGFB2
TGFB2 activates BMP7
BMP7 activates TGFB2
TGFB2 associated_with E2F5

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