| Gene Symbol | BMP7 |
| Function | encodes a member of the TGF-beta superfamily of signaling molecules. |
| Primary Expression | adult tissues and has important roles in bone formation, kidney development, tissue repair, and neuroprotection |
| Amino Acids | 431 aa |
| Pathways | MAPK pathway, PI3K |
| Ensembl ID | ENSG00000101144 |
| GeneCards | BMP7 |
| Human Protein Atlas | BMP7 |
| Precursor protein | ~431 amino acids |
| Signal peptide | N-terminal targeting sequence |
| Prodomain | Removed during processing |
| Mature dimer | Active form (~115 amino acids per monomer) |
| Homodimers | Most common active form |
| Heterodimers | Can pair with BMP2 or BMP4 for enhanced activity |
| Disulfide bonds | Cysteine-mediated dimerization |
| Associated Diseases | Als, Alzheimer, Autoimmune, Cancer, Carcinoma, Diabetes |
| Interactions | AND, BMP4, BMPR1B, ERK, ERK1, TGFB2 |
| KG Connections | 62 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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