| Gene Symbol | CDKN2B |
| Full Name | Cyclin-Dependent Kinase Inhibitor 2B (p15/INK4b) |
| Chromosome | 9p21.3 |
| Protein Type | Kinase |
| Function | p15 binds to and inhibits cyclin-dependent kinases 4 and 6 (CDK4/6), which are required for G1 phase progression. |
| Pathways | TGF-β, TGF-β signaling |
| UniProt ID | [P42772](https://www.uniprot.org/uniprot/P42772) |
| Ensembl ID | ENSG00000147883 |
| OMIM | 600431 |
| GeneCards | CDKN2B |
| Human Protein Atlas | CDKN2B |
| Associated Diseases | Cancer, Carcinoma, Ms, Senescence, Tumor |
| Interactions | CANCER, CDKN2B-AS1, C-MYC, CYCLIN D1, LNCRNA, MYC |
| KG Connections | 59 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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