gene 1,671 words KG: E2F5
Contents

E2F5 Gene

🧬 Gene Info
Gene SymbolE2F5
Full NameE2F Transcription Factor 5
Chromosome8q21.3
Protein FamilyE2F transcription factor family
Protein TypeTranscription factor, Cell cycle regulator
Functionencodes E2F Transcription Factor 5, a member of the E2F family of transcription factors that play critical roles in regulating cell cycle progression, cellular differentiation, and apoptosis
Primary Expressiona tissue-specific manner and has been shown to function primarily as a transcriptional repressor in differentiated cells
Exons7 coding exons
UniProt IDQ504Y5
NCBI Gene ID1883
Ensembl IDENSG00000158636
OMIM600223
GeneCardsE2F5
Human Protein AtlasE2F5
Gene LengthApproximately 12 kb
Associated DiseasesCancer, Carcinoma, Ms, Tumor
KG Connections21 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.92
Senescence-Activated NAD+ Depletion Rescue
Score: 0.76
Senescence-Associated Myelin Lipid Remodeling
Score: 0.73
Senescence-Induced Lipid Peroxidation Spreading
Score: 0.73
Astrocyte-Mediated Neuronal Epigenetic Rescue
Score: 0.73

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (11)

Neurodegeneration
disease · KG edge: implicated_in
Tumor Necrosis Factor (TNF)
entity · KG edge: associated_with
Genes
index · KG edge: associated_with
BMP2 — Bone Morphogenetic Protein 2
gene · KG edge: associated_with
BMP4 Gene (Bone Morphogenetic Protein 4)
gene · KG edge: associated_with

Knowledge Graph (12 edges)

TGFBR2 associated_with E2F5
BMP4 associated_with E2F5
MYC associated_with E2F5
E2F5 associated_with CDKN2B
E2F5 associated_with TGFBR1
E2F5 associated_with BMP2
E2F5 associated_with TGFB2
E2F5 associated_with BMP7
BMP2 associated_with E2F5
TGFBR1 associated_with E2F5

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