gene 947 words KG: SYT1
Contents

SYT1 — Synaptotagmin 1

🧬 Gene Info
Gene SymbolSYT1
Full NameSynaptotagmin 1
Chromosome12q21.2
FunctionSynaptotagmin 1 is a presynaptic vesicular protein that functions as the calcium sensor for fast neurotransmitter release
Amino Acids421 aa
PathwaysApoptosis, Autophagy, autophagy pathway, oxidative stress response
UniProt IDP21579
NCBI Gene ID6856
Ensembl IDENSG00000130147
OMIM185580
GeneCardsSYT1
Human Protein AtlasSYT1
Associated DiseasesAlzheimer, neurodegeneration
Known Drugs/Compoundsrapamycin
InteractionsACTB, Actin, AD, ALZHEIMER, ALZHEIMER DISEASE, AMPK
KG Connections227 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (5)

Synaptic Vesicle Tau Capture Inhibition
Score: 0.58
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Extracellular Vesicle Biogenesis Modulation
Score: 0.58

Related Analyses (2)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (5)

AAV-LRRK2 IND-Enabling Study Design
clinical · proposed · Score: 0.40
cGAS-STING Pathway Validation Study in Parkinson's Disease
clinical · proposed · Score: 0.40
Epigenetic Dysregulation Validation in Parkinson's Disease
clinical · proposed · Score: 0.40
AAV-LRRK2 Gene Therapy IND-Enabling Study Design
clinical · proposed · Score: 0.40
Multiscale Computational Modeling of Protein Aggregation Kin
validation · proposed · Score: 0.40

See Also (15)

AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: activates
Genes
index · KG edge: associated_with
ACTB Gene
gene · KG edge: activates
ATG7 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

ACTB activates SYT1
LAMP1 associated_with SYT1
MTOR associated_with SYT1
LC3 associated_with SYT1
TUBB3 associated_with SYT1
ATG7 activates SYT1
JUN activates SYT1
SQSTM1 associated_with SYT1
MAP2 associated_with SYT1
SYN1 associated_with SYT1

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