Contents

RAB9A

🧬 Gene Info

Gene Symbol	RAB9A
Aliases	RAB GTPase 9A
Function	is a member of the RAB GTPase family that functions as a molecular switch controlling intracellular membrane trafficking.
Molecular Weight	23 kDa
Amino Acids	201 aa
Pathways	Mtor, Autophagy, Amyloid, epigenetic regulation, autophagy pathway
Ensembl ID	ENSG00000123595
GeneCards	RAB9A
Human Protein Atlas	RAB9A
Active state (RAB9A-GTP)	Membrane-associated, recruits effector proteins
Inactive state (RAB9A-GDP)	Cytosolic, available for recycling to membranes
GEFs	Promote GDP release and GTP binding (activation)
GAPs	Accelerate GTP hydrolysis (inactivation)
GDIs	Extract GDP-bound RAB from membranes
Lysosomal biogenesis	Delivery of newly synthesized lysosomal enzymes
Associated Diseases	Cancer, Cardiovascular, Ischemia, Ms, Neurodegeneration, Parkinson
Known Drugs/Compounds	rapamycin
Interactions	AMPK, AMYLOID, AR, ATG, ATP6AP2, BCL2
KG Connections	151 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

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