gene 2,602 words KG: P2RY2
Contents

P2RY2 (Purinergic Receptor P2Y2)

🧬 Gene Info
Gene SymbolP2RY2
Full NamePurinergic Receptor P2Y2
Chromosome11q13.2
Protein FamilyP2Y receptor family (GPCR)
Protein TypeReceptor
Functionis a unique member of the P2Y receptor family because it is activated by both ATP and UTP with similar potency, making it a central sensor of cellular stress and tissue damage.
Molecular Weight43 kDa
Exons2
UniProt IDQ9ULL8
NCBI Gene ID5029
Ensembl IDENSG00000165326
OMIM173415
GeneCardsP2RY2
Human Protein AtlasP2RY2
Associated Diseasesepilepsy
KG Connections67 knowledge graph edges
DatabasesGeneCardsHPASTRING

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Knowledge Graph

Related Hypotheses (5)

Purinergic Signaling Polarization Control
Score: 0.71
Purinergic P2Y12 Inverse Agonist Therapy
Score: 0.70
Microglial Purinergic Reprogramming
Score: 0.70
Synaptic Vesicle Tau Capture Inhibition
Score: 0.58
Gap Junction Hemichannel Modulation for Controlled Mitochond
Score: 0.29

Related Analyses (4)

4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Astrocytes
cell · KG edge: associated_with
Microglia
cell · KG edge: associated_with
Astrocytes
entity · KG edge: associated_with
Microglia in Neurodegeneration
entity · KG edge: associated_with
astrocyte-neuron-metabolic-coupling-parkinsons
general · KG edge: associated_with

Knowledge Graph (12 edges)

PANX1 regulates P2RY2
S100B regulates P2RY2
RELB regulates P2RY2
P2RY1 regulates P2RY2
CASP3 regulates P2RY2
SOCS3 regulates P2RY2
TRPA1 regulates P2RY2
CXCL2 regulates P2RY2
SNAP25 regulates P2RY2
P2RX7 regulates P2RY2

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