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gene 2,283 words KG: HSP90AB1
Contents

HSP90AB1 Gene

🧬 Gene Info
Gene SymbolHSP90AB1
Chromosome6p21.1
Molecular Weight90 kDa
Amino Acids724 aa
Exons11
PathwaysLipid Metabolism, Autophagy, Blood-Brain Barrier, Mapk, Apoptosis
GeneCardsHSP90AB1
Human Protein AtlasHSP90AB1
Associated DiseasesAging, Als, Cancer, Ms
InteractionsACTB, ACTG1, ATP5A1, CANCER, CCT2, CD8
KG Connections188 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (10)

GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.75Cross-Seeding Prevention Strategy
Score: 0.69Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68Glycine-Rich Domain Competitive Inhibition
Score: 0.64Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62VCP-Mediated Autophagy Enhancement
Score: 0.59Synaptic Vesicle Tau Capture Inhibition
Score: 0.58HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57Cryptic Exon Silencing Restoration
Score: 0.53RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
Score: 0.47

Related Analyses (6)

SEA-AD Gene Expression Profiling — Allen Brain Cell Atlas
neurodegeneration · completedTDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archivedRNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archivedPerivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archivedTau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (15)

Apoptosis in Neurodegeneration
entity · KG edge: expressed_inAutophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_withACTB Gene
gene · KG edge: interacts_withACTG1 Gene
gene · KG edge: interacts_withAKT1 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

PLIN1 associated_with HSP90AB1
HSP90AB1 associated_with MAP1LC3B
FYN expressed_in HSP90AB1
VCP expressed_in HSP90AB1
CTNNB1 expressed_in HSP90AB1
EGFR expressed_in HSP90AB1
HSP90AA1 expressed_in HSP90AB1
APP expressed_in HSP90AB1
HSP90AB1 expressed_in MDM2
HSP90AB1 expressed_in HSF1

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