gene 699 words KG: DNAJC10
Contents

DNAJC10 Gene

🧬 Gene Info
Gene SymbolDNAJC10
Full NameDnaJ Heat Shock Protein Family (Hsp40) Member C10
AliasesERdj5
Protein TypeChaperone
FunctionDNAJC10/ERdj5 possesses multiple domains and functions
Primary Expressioncortex, hippocampus, and various brain regions - Cellular Localization: ER lumen, with some
Subcellular Localizationthe endoplasmic reticulum (ER) where it plays critical roles in protein folding, quality control, and ER-associated degr
Molecular Weight90.6 kDa
Amino Acids70 aa
GeneCardsDNAJC10
Human Protein AtlasDNAJC10
J DomainBinds to Hsp70 family proteins and stimulates their ATPase activity
Client Binding DomainRecognizes and binds to misfolded proteins
Thioredoxin DomainsContains two thioredoxin-like domains with redox activity
ER LocalizationContains an ER retention signal (KDEL or RDEL)
Associated Diseasesneurodegeneration
KG Connections39 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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