gene 695 words KG: FOS
Contents

FOS Gene

🧬 Gene Info
Gene SymbolFOS
Full NameFBJ Murine Osteosarcoma Viral Oncogene Homolog
Chromosome14q24.3
Protein TypeTranscription Factor
FunctionFOS is an immediate-early gene encoding a leucine zipper transcription factor.
Molecular Weight40.6 kDa
PathwaysImmune Response, Neurogenesis, Nf-Kb, Nf-Κb, Synaptic Plasticity
UniProt IDP01100
NCBI Gene ID2353
Ensembl IDENSG00000170345
OMIM164810
GeneCardsFOS
Human Protein AtlasFOS
Activity-dependent transcriptionResponds to neuronal firing and calcium influx
AP-1 complex formationHeterodimers with JUN family proteins (c-JUN, JUNB, JUND)
Associated DiseasesAls, Alzheimer, Atherosclerosis, Cancer, Ischemia, Ms
Known Drugs/Compoundspokeweed mitogen
InteractionsActin, AKT1, ALZHEIMER, ALZHEIMER'S DISEASE, AND, ANXIETY
KG Connections486 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (25)

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Score: 0.66
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Epigenetic Memory Reprogramming for Alzheimer's Disease
Score: 0.61
HSP90-Tau Disaggregation Complex Enhancement
Score: 0.57
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
← Prevpg 2/2

Related Analyses (8)

Epigenetic reprogramming in aging neurons
neurodegeneration · archived
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What are the mechanisms by which gut microbiome dysbiosis in
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Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

See Also (15)

Alzheimer Indonesia
institution · KG edge: associated_with
BCL2 Gene
gene · KG edge: therapeutic_target
AKT1 Gene
gene · KG edge: interacts_with
BMAL1 (ARNTL) Gene
gene · KG edge: activates
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: regulates

Knowledge Graph (12 edges)

FOS contributes_to AP1
EGF activates FOS
PIEZO1 activates FOS
SRC activates FOS
EGFR activates FOS
JUN activates FOS
pokeweed mitogen activates FOS
P38 activates FOS
FOS activates SRC
JUN interacts_with FOS

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