| Gene Symbol | DKK1 |
| Full Name | Dickkopf WNT Signaling Pathway Inhibitor 1 |
| Chromosome | 10q21.1 |
| Function | This prevents formation of the Wnt-Frizzled-LRP5/6 ternary complex and downstream β-catenin stabilization. |
| Primary Expression | Brain (low), Bone, Kidney, Liver |
| Amino Acids | 305 aa |
| Pathways | WNT Signaling, Wnt Signaling, Wnt, Wnt signaling |
| UniProt ID | O94907 |
| NCBI Gene ID | 2698 |
| Ensembl ID | ENSG00000107957 |
| OMIM | 605386 |
| GeneCards | DKK1 |
| Human Protein Atlas | DKK1 |
| Associated Diseases | Alzheimer, dementia, depression |
| Interactions | App, DNMT1, JNK, Leptin, NESTIN, PS1 |
| KG Connections | 161 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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