gene 2,666 words KG: CD36
Contents

CD36 Gene

🧬 Gene Info
Gene SymbolCD36
AliasesComprehensive review of CD36 scavenger receptor
Chromosome7q21.11
Protein TypeGene
Functionis a multifunctional class B scavenger receptor encoded by the CD36 gene located on chromosome 7q21.
Molecular Weight88 kDa
Amino Acids472 aa
Exons15
PathwaysAmyloid, Cholesterol, Epigenetic, Ferroptosis, Lipid Metabolism
GeneCardsCD36
Human Protein AtlasCD36
Associated DiseasesALS, Alzheimer, Atherosclerosis, Cancer, Inflammation, Myocardial Infarction
InteractionsABCA1, ABCG1, AGING, AKT, ALZHEIMER, ALZHEIMER'S DISEASE
KG Connections570 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (33)

Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70
Axonal RNA Transport Reconstitution
Score: 0.70
Sphingomyelin Synthase Activators for Raft Remodeling
Score: 0.69
Ganglioside Rebalancing Therapy
Score: 0.69
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.67
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.66
Ephrin-B2/EphB4 Axis Manipulation
Score: 0.64
TREM2-Dependent Microglial Senescence Transition
Score: 0.62
TREM2-mediated microglial tau clearance enhancement
Score: 0.62
SIRT6-NAD+ Axis Enhancement Therapy
Score: 0.61
TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58
Fractalkine Axis Amplification via CX3CR1 Positive Allosteri
Score: 0.56
← Prevpg 2/2

Related Analyses (11)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
APOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

Related Experiments (2)

Ketogenic diet fat threshold analysis in wild-type mice
validation · proposed · Score: 0.90
Protein expression analysis and cell migration assays in car
exploratory · proposed · Score: 0.88

See Also (6)

acc-chronic-pain
cell_type · KG edge: expressed_in
AMPK (AMP-Activated Protein Kinase)
entity · KG edge: activates
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activates
ABCG1 Gene
gene · KG edge: inhibits
Alzheimer Indonesia
institution · KG edge: activates

Knowledge Graph (12 edges)

CD36 interacts_with oxLDL
SOAT1 activates CD36
DGAT1 activates CD36
APOA1 activates CD36
CD36 activates PLIN2
CD36 activates NR1H3
CD47 associated_with CD36
TLR2 associated_with CD36
CD36 interacts_with CMKLR1
CD36 associated_with RAGE

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