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gene 2,666 words KG: CD36
Contents

CD36 Gene

🧬 Gene Info
Gene SymbolCD36
AliasesComprehensive review of CD36 scavenger receptor
Chromosome7q21.11
Protein TypeGene
Functionis a multifunctional class B scavenger receptor encoded by the CD36 gene located on chromosome 7q21.
Molecular Weight88 kDa
Amino Acids472 aa
Exons15
PathwaysAmyloid, Cholesterol, Epigenetic, Ferroptosis, Lipid Metabolism
GeneCardsCD36
Human Protein AtlasCD36
Associated DiseasesALS, Alzheimer, Atherosclerosis, Cancer, Inflammation, Myocardial Infarction
InteractionsABCA1, ABCG1, AGING, AKT, ALZHEIMER, ALZHEIMER'S DISEASE
KG Connections570 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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Knowledge Graph

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (33)

APOE Isoform Conversion Therapy
Score: 0.72Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72Gamma entrainment therapy to restore hippocampal-cortical sy
Score: 0.95Oligodendrocyte Protectin D1 Mimetic for Myelin Resolution
Score: 0.68ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.89Noradrenergic-Tau Propagation Blockade
Score: 0.71APOE-Dependent Autophagy Restoration
Score: 0.89Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.79Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam
Score: 0.79Competitive APOE4 Domain Stabilization Peptides
Score: 0.78APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.76Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.76APOE Isoform Expression Across Glial Subtypes
Score: 0.74APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.74APOE-TREM2 Interaction Modulation
Score: 0.74Metabolic Switch Targeting for A1→A2 Repolarization
Score: 0.73Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.72Metabolic Circuit Breaker via Lipid Droplet Modulation
Score: 0.71Microglial Efferocytosis Enhancement via GPR32 Superagonists
Score: 0.70
pg 1/2Next →

Related Analyses (11)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archivedAstrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archivedAPOE4 structural biology and therapeutic targeting strategie
neurodegeneration · archivedNeuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

Related Experiments (2)

Ketogenic diet fat threshold analysis in wild-type mice
validation · proposed · Score: 0.90Protein expression analysis and cell migration assays in car
exploratory · proposed · Score: 0.88

See Also (6)

acc-chronic-pain
cell_type · KG edge: expressed_inAMPK (AMP-Activated Protein Kinase)
entity · KG edge: activatesAmyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activatesABCG1 Gene
gene · KG edge: inhibitsAlzheimer Indonesia
institution · KG edge: activates

Knowledge Graph (12 edges)

CD36 interacts_with oxLDL
SOAT1 activates CD36
DGAT1 activates CD36
APOA1 activates CD36
CD36 activates PLIN2
CD36 activates NR1H3
CD47 associated_with CD36
TLR2 associated_with CD36
CD36 interacts_with CMKLR1
CD36 associated_with RAGE

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