gene 1,919 words KG: CCR1
Contents

CCR1

🧬 Gene Info
Gene SymbolCCR1
Full NameC-C Chemokine Receptor Type 1
Chromosome3p21.31
Protein FamilyChemokine receptors (GPCR family)
Protein TypeReceptor
Functionencodes a G protein-coupled receptor that binds multiple CC chemokines including CCL3 (MIP-1α), CCL5 (RANTES), CCL7 (MCP-3), CCL14 (HCC-1), and CCL15 (HCC-2).
Amino Acids355 aa
Exons5
PathwaysNF-κB
UniProt IDP32246
NCBI Gene ID1230
Ensembl IDENSG00000163631
OMIM601626
GeneCardsCCR1
Human Protein AtlasCCR1
Associated DiseasesAlzheimer's disease, Parkinson's disease, Multiple sclerosis, ALS
InteractionsCCL2, CCL3, CCL5, CCR5, CXCL10, CXCR3
KG Connections107 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

SASP-Mediated Cholinergic Synapse Disruption
Score: 0.76

Related Analyses (2)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (1)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40

See Also (14)

AIF1 Gene
gene · KG edge: associated_with
C1QA Gene
gene · KG edge: associated_with
C1QB — Complement Component 1Q Beta
gene · KG edge: associated_with
C3AR1 Gene
gene · KG edge: associated_with
CCL3 Gene
gene · KG edge: inhibits

Knowledge Graph (12 edges)

CCR1 regulates MRC1
CCR1 regulates C1QB
CCR1 regulates CD38
CCR1 regulates CD163
CCR1 regulates CXCL10
CCR1 associated_with C1QB
CCR1 associated_with CD4
CCR1 associated_with AIF1
CCR1 associated_with CD163
CCR1 associated_with CYBB

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