| Gene Symbol | CCR5 |
| Aliases | CCR5 chemokine receptor |
| Protein Type | Gene |
| Function | CCR5 is a seven-transmembrane G protein-coupled receptor that binds CCL3 (MIP-1α), CCL4 (MIP-1β), and CCL5 (RANTES). |
| Molecular Weight | 46 kDa |
| Amino Acids | 352 aa |
| Pathways | MAPK, PI3K |
| UniProt ID | P51681 |
| GeneCards | CCR5 |
| Human Protein Atlas | CCR5 |
| Immune cell recruitment | Chemoattraction of monocytes, T cells, microglia |
| Neuroinflammation modulation | Mediates inflammatory responses in CNS |
| HIV co-receptor | Primary co-receptor for R5-tropic HIV-1 |
| Neuroprotection | Some evidence for neuroprotective effects |
| Pain modulation | Involved in neuropathic pain signaling |
| Associated Diseases | Als, Alzheimer, Inflammation, Neuroinflammation, Ptsd |
| Interactions | adcy2, ADCY2, AKT, ALZHEIMER, ALZHEIMER'S DISEASE, AND |
| KG Connections | 278 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
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